DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ddx1 and Prp5

DIOPT Version :10

Sequence 1:NP_524212.2 Gene:Ddx1 / 40457 FlyBaseID:FBgn0015075 Length:727 Species:Drosophila melanogaster
Sequence 2:NP_573020.2 Gene:Prp5 / 32464 FlyBaseID:FBgn0030631 Length:1224 Species:Drosophila melanogaster


Alignment Length:454 Identity:129/454 - (28%)
Similarity:188/454 - (41%) Gaps:97/454 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   251 GNGFVGACQAGPEHSKA--NPITGPAAGAPSAKPAPNAPQAIIMEPSRELAEQTYNQIEKFKYHL 313
            |...:|..:.|...:.|  .|:.......||.:....| .||||.|:|||..|....|.||...|
  Fly   547 GRDLIGIAKTGSGKTLAFILPMFRHILDQPSMEDGDGA-IAIIMAPTRELCMQIGKDIRKFSKSL 610

  Fly   314 SNPEVRSLLLIGGVRLEEQKAQLMQGTHIVVGTPGRLEEMI--NSGLVL-LTHCRFFVLDEADAL 375
            .   :|.:.:.||..:.||.|:|.:|..|:|.||||:.:|:  |||.|. |....:.||||||.:
  Fly   611 G---LRPVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRM 672

  Fly   376 LKQGYTELIDRLHKQIPKITSDGRRLQMVVCSATLHAFEVKKMAERLMHFPTWVDLKGEDAV-PE 439
            ...|:...:.|:   |..:..|   .|.|:.|||... :::.:|.|::..|..|.:.|...| .|
  Fly   673 FDMGFEPQVMRI---IDNVRPD---RQTVMFSATFPR-QMEALARRILKKPIEVIVGGRSVVCKE 730

  Fly   440 TVHHVVCLVDPQMDTTWQSLRQPIGTDGVHDRDNVHPGNHSKETLSQAVKLLK--GEYCVHAIDK 502
            ...|||.|.|.                                  ::..|||:  |.|       
  Fly   731 VEQHVVILNDD----------------------------------AKFFKLLELLGIY------- 754

  Fly   503 HNMDRAIIFCRTKQDCDNLERFLRQRGGKHYSCVCLHGDRKPQERKENLEMFKRQQVKFLICTDV 567
            ......|:|...:::.|.|.|.|.:..   |.|:.|||.....:|...:..||..:|:.||.|.|
  Fly   755 QEAGSIIVFVDKQENADILLRDLMKAS---YPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSV 816

  Fly   568 AARGLDITGLPFMINVTLPDDKTNYVHRIGRVGRAERMGLAISLVATVPEKVWYHGEWCKSRGRS 632
            ||||||:..|..::|..:|:...:||||.||.|||.:.|.|.:.:  .||:..|.|:..::...|
  Fly   817 AARGLDVKDLILVVNYDVPNHYEDYVHRCGRTGRAGKKGSAYTFI--TPEQSRYAGDIIRAMDLS 879

  Fly   633 CNNTNLTEVRGCCIWYNEPNLLAEVEDHLNITIQQVDKTMDVPVNDFDGKVVYGQKNLRTGSGY 696
               ..|.......:| .|...|.|.|                      ||.|:      ||.|:
  Fly   880 ---GTLIPAELQALW-TEYKALQEAE----------------------GKTVH------TGGGF 911

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ddx1NP_524212.2 DEAD-like_helicase_N 4..>73 CDD:475120
SPRY_DDX1 91..242 CDD:293933
SrmB 283..613 CDD:440279 105/335 (31%)
Prp5NP_573020.2 Trypan_PARP <291..383 CDD:368653
DEAD-like_helicase_N 454..899 CDD:475120 121/412 (29%)
KH-I_DDX46 1121..1223 CDD:411901
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.