Protein Alignment Ddx1 and mahe

DIOPT Version :10

• Sequence 1: NP_524212.2
• Gene: Ddx1 / 40457
• FlyBaseID: FBgn0015075
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_572424.1
• Gene: mahe / 31707
• FlyBaseID: FBgn0029979
• Length: 945
• Species: Drosophila melanogaster
• Alignment Length: 728
• Identity: 164/728 - (22%)
• Similarity: 257/728 - (35%)
• Gaps: 233/728 - (32%)

  Fly    39 GGDVLMAAETGSGKTGAFCLPILQIVWETLRDLEEGKAGKGGAIGGAVTPWTMSFFDRGNALAVT 103
            ||..:..|.|.:|.. .|..|...:.:.....|..|.||.||.     .|:...     |.:|..
  Fly    55 GGAGINGAATAAGSM-HFGQPYGVMTYGIQNGLGMGAAGSGGG-----NPYRQQ-----NGVAFA 108

  Fly   104 PDGLRCQSREFKEWHGCRATTGVRGKGKFYFEATVTDEGLCRVGWSTQQANLDLGTCRM-----G 163
            .:||           |..|..|..|.|                |:..|:........|.     |
  Fly   109 GNGL-----------GGGAGGGSGGSG----------------GYGGQRGKNPTYAQRYQKPNNG 146

  Fly   164 FGFGGTGKKSNNRQFDDYGEAFGKADVIGCLLDLKNQEVS---------------------FTKN 207
            .|..| |.:|||     |..|     .:|.|...:..|:.                     |.|:
  Fly   147 AGVAG-GYQSNN-----YNAA-----ALGMLSKEERAEIQREKAKNPGRNLVKPKWENLEPFLKD 200

  Fly   208 GQNLGVAFRLPDNLAK-----------------------------ETFYPAVVLKNAEMQFNFGK 243
            ..|:.     |:.|||                             |:..||.|::..:.| .|.|
  Fly   201 FYNIH-----PNTLAKSEQQVAEIRRELEITVSGNELPHPVVSFEESSLPAHVIEEMKRQ-GFTK 259

  Fly   244 TDFKYA-------PGNGFVGACQAGPEHSKANPITGPAAGAPSAKP---APNAPQAIIMEPSREL 298
            .....:       .|...||..|.|...:.|..:  ||......:|   ....|.|:::.|:|||
  Fly   260 PTAIQSQGWPIALSGRDLVGIAQTGSGKTLAYML--PAIVHIGNQPPIIRGEGPIALVLAPTREL 322

  Fly   299 AEQTYNQIEKFKYHLSNPEVRSLLLIGGVRLEEQKAQLMQGTHIVVGTPGRLEEMINSGLVLLTH 363
            |:|..:.:..:. ||..||:|...:.||.....|...|.:|..:::.|||||.:.:.:....|..
  Fly   323 AQQIQSVVRDYG-HLCKPEIRHTCIFGGSSKVPQARDLDRGVEVIIATPGRLIDFLENRNTNLQR 386

  Fly   364 CRFFVLDEADALLKQGYTELIDRLHKQIPKITSDGRRLQMVVCSATLHAFEVKKMAERLMHFPTW 428
            |.:.||||||.:|..|:.   .::.|.|.:|..|   .|:|:.||
  Fly   387 CTYLVLDEADRMLDMGFE---PQIRKIIEQIRPD---RQVVMWSA-------------------- 425

  Fly   429 VDLKGEDAVPETVHHVVCLVDPQMDTTWQSLRQPIGTDGVHDRDNVHPG------NHS-KETLSQ 486
                                      ||....|.:..|.::|...::.|      ||: ::.:..
  Fly   426 --------------------------TWPKEVQALAGDFLNDYIQINIGSMNLSANHNIRQIVEI 464

  Fly   487 AVKLLKGEYCVHAIDK--------HNMDRAIIFCRTKQDCDNLERFLRQRGGKHYSCVCLHGDRK 543
            ..::.|.:..|..:::        :|.::.|:|..||...:::.:.:|..|   |:...:|||:.
  Fly   465 CTEIEKPQRLVCLLNEISPIKNSGNNGNKIIVFVETKIKVEDILQIIRAEG---YNATSIHGDKT 526

  Fly   544 PQERKENLEMFKRQQVKFLICTDVAARGLDITGLPFMINVTLPDDKTNYVHRIGRVGRAERMGLA 608
            ..||...|:.|:..:...||.||||:||||:..|.::||...|:...||||||||.||.:::|.|
  Fly   527 QNERDSVLKDFRNGKSNILIATDVASRGLDVEDLQYVINYDYPNSSENYVHRIGRTGRCQQLGTA 591

  Fly   609 ------------------------------ISLVATVPEKVWYHG--EWCKSRGRSCN---NTNL 638
                                          :.|..::|....|.|  .|..:.|...|   |..:
  Fly   592 YTFFTPDNAKQARELISVLEEAGQTPSQALLDLARSMPSSGGYRGNKRWNNNSGGDRNTGGNNGI 656

  Fly   639 TEVRGCCIWYNEP 651
            .:.|.     |.|
  Fly   657 YQQRN-----NNP 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddx1	NP_524212.2	DEAD-like_helicase_N	4..>73	CDD:475120	8/33 (24%)
		SPRY_DDX1	91..242	CDD:293933	36/205 (18%)
		SrmB	283..613	CDD:440279	93/374 (25%)
mahe	NP_572424.1	DEAD-like_helicase_N	136..656	CDD:475120	136/594 (23%)