DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment olf413 and moxd1l

DIOPT Version :9

Sequence 1:	NP_001262204.1	Gene:	olf413 / 40453	FlyBaseID:	FBgn0037153	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_001121997.1	Gene:	moxd1l / 553484	ZFINID:	ZDB-GENE-060126-3	Length:	564	Species:	Danio rerio

Alignment Length:	545	Identity:	156/545 - (28%)
Similarity:	252/545 - (46%)	Gaps:	71/545 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 PIWDHAIDLNDDFRILWQI--INQDITFEIQARTLGYVGFGFSPDGNLAGADMAIGWVDKGQTYF 169
            |..:| :||..:.::.|..  |...|.|::...|.|::.||.||:|.:.|||:.||.||...|||
Zfish    25 PFSEH-LDLEHNVQLKWGFDKIQGTILFQLSVNTSGWISFGLSPNGGMTGADIVIGGVDNKGTYF 88

  Fly   170 QDRHVTRNGDPEPVVDPSQDYMLMLGYENATHTVLRFRRKLDTCDPSHDIAITNDTMRLLYMY-H 233
            .|||..  |:..||||..|:|.|:...|:...||::|:|.:::|| .:|:.:|...|:|:|.| .
Zfish    89 TDRHAL--GNSMPVVDQKQNYKLLSLSESDGKTVMKFQRSIESCD-ENDLPVTILPMKLIYAYGE 150

  Fly   234 AQDPPHGSVRPGTLPDPARAFRPYRPMVLMQRAQLPMPSPTHDERVRVLELRNEDVELPAGDLPL 298
            ..|..:...:.||        :....:..|.||.|        ......::..|:..|||.. ..
Zfish   151 TDDISYHKAQRGT--------KEVNLLKYMPRASL--------SNATYFDITMENFMLPANQ-TY 198

  Fly   299 FWCKMFKLEDINRKHHLIRYEPIYDSSSSVHYLQHITLHECQGAHAELEEMAREQGRPCLGARSI 363
            :.||..:....:.|.|:.|.||:..:...||   |:.|:.|.....|..|:      .|.....
Zfish   199 YHCKTARAPTFDSKQHIYRIEPVITNYDLVH---HLLLYRCPPTVTEPLEL------ECYTKTE- 253

  Fly   364 PLACNAIVASWSRGSEGFTYPHEAGYPIESRQAK-YYLMETHYNNLKPDFAQLHARQMADNSGLK 427
              .|...:|.|..|...|.:|..||.||...... :|.:|.||||:.....::      |:|||:
Zfish   254 --RCMETIAVWGVGGGDFEFPEVAGLPIGGNVGDFFYRLEVHYNNVNKTAGRV------DSSGLR 310

  Fly   428 IYFTHVLRPNDAGTLSIGMDPNWRHIIPPGQKRVVSEGQCIEDCTGYAFPQ-----QGINIFAVM 487
            .|:|..||.:|||.|..|:.....:.|||..|..::.|.|  |.|  ..|:     ..:.:|:||
Zfish   311 FYYTSKLRQHDAGILMTGLAVIPSYAIPPKAKSFLTYGMC--DTT--YIPKVLETANDLQVFSVM 371

  Fly   488 MRTHQIGKEVKLRQIRQTEELPPIAHDSNIDVAYQDFRRLPQSVHSMPGDRLIAECIYDSSSRKA 552
            |.||..|::|::...|:.:::..:|.|.|.:..:|....|.::.....||:|:.||.|::.:|..
Zfish   372 MHTHLAGRKVRVGHFREGKQIDLLAVDENYNFEFQQVTNLGKTKTVKLGDKLLVECTYNTENRNT 436

  Fly   553 ITLGGLTMKEESCTVLTLYYPRQKKLTTCHSLPSLPTVLHSLGIEQLATDSNPVLISSPPELAGM 617
            :|.|||:..:|.|.....|||.. .|:.|.|||...:::..:|    |.|:...|.
Zfish   437 LTQGGLSTSDEMCLAFLFYYPAM-NLSGCESLPHFSSLVSEMG----AGDTGTWLY--------- 487

  Fly   618 TLEARLISYDW-ENQFGEFQEATRK 641
                .:.:..| ::...|:|:..:|
Zfish   488 ----MMNTMAWNDSSINEYQQTLKK 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
olf413	NP_001262204.1	DOMON_DOH	111..243	CDD:187689	49/134 (37%)
		Cu2_monooxygen	282..407	CDD:279429	33/125 (26%)
		Cu2_monoox_C	438..583	CDD:281675	46/149 (31%)
moxd1l	NP_001121997.1	DOMON_DOH	30..162	CDD:187689	48/134 (36%)
		Cu2_monooxygen	182..299	CDD:279429	35/129 (27%)
		Cu2_monoox_C	321..466	CDD:281675	46/149 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592017
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3568
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59784
OrthoDB	1	1.010	-	-		D1472750at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.860