Protein Alignment Act79B and ACTRT1

DIOPT Version :10

• Sequence 1: NP_524210.1
• Gene: Act79B / 40444
• FlyBaseID: FBgn0000045
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_612146.1
• Gene: ACTRT1 / 139741
• HGNCID: 24027
• Length: 376
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 178/372 - (47%)
• Similarity: 253/372 - (68%)
• Gaps: 3/372 - (0%)

  Fly     5 EASALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILSLK 69
            :..|::.|||||:||||.:|:..||.|..|::|..:....:..:.|| .:||.||..|...|.|.
Human     8 DVPAVIFDNGSGLCKAGLSGEIGPRHVISSVLGHCKFNVPLARLNQK-YFVGQEALYKYEALHLH 71

  Fly    70 YPIEHGIITNWDDMEKVWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMY 134
            ||||.|::|.||||||:|.|.|..||.|.|.:.|||:||..|||:..|||:.::|||||:.|..|
Human    72 YPIERGLVTGWDDMEKLWKHLFERELGVKPSQQPVLMTEPSLNPREIREKLAEMMFETFSVPGFY 136

  Fly   135 VAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGY 199
            ::..||.:||||...||:|:||||||:.||||:|||:||||:.:|.:||||:|::|.::|...|:
Human   137 LSNHAVAALYASACVTGLVVDSGDGVTCTVPIFEGYSLPHAVTKLCMAGRDITEHLTRLLFASGF 201

  Fly   200 SFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRTPEALFQ 264
            :|.....:.:|.:|||||||:||:.|:|:..:..  .:..:|.||||.||..|:|.::.||.||.
Human   202 NFPCILNKAVVNNIKEKLCYIALEPEKELRKSRG--EVLGAYRLPDGHVIHFGDELYQVPEVLFA 264

  Fly   265 PSFLGMESCGIHETVYQSIMKCDVDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTIKIK 329
            |..||:.|.|:.:.|..||||||.||:..|||:.|||||||:.||:.:|:.||:..||.....||
Human   265 PDQLGIHSPGLSKMVSSSIMKCDTDIQNKLYADIVLSGGTTLLPGLEERLMKEVEQLASKGTPIK 329

  Fly   330 IIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF 376
            |.|.|:|.:|.|||.||:.|:|:|:|||::..::.|.|..:|.|:||
Human   330 ITASPDRCFSAWIGASIMTSMSSFKQMWVTSADFKEYGTSVVQRRCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act79B	NP_524210.1	ASKHA_NBD_actin	7..371	CDD:466823	174/363 (48%)
ACTRT1	NP_612146.1	ASKHA_NBD_actin_Arp-T1-3	10..367	CDD:466848	173/359 (48%)