Protein Alignment eg and nr1d1

DIOPT Version :10

• Sequence 1: NP_524206.1
• Gene: eg / 40428
• FlyBaseID: FBgn0000560
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: NP_991292.2
• Gene: nr1d1 / 494487
• ZFINID: ZDB-GENE-050105-1
• Length: 637
• Species: Danio rerio
• Alignment Length: 371
• Identity: 90/371 - (24%)
• Similarity: 134/371 - (36%)
• Gaps: 132/371 - (35%)

  Fly     4 LCKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNIAAIAGCKHNGDCVINKKNRTACKACRLRKCLL 68
            ||||||:.|:|||:|...|||||.||.|:.........|..|..|.|.:.||..|:.||.:|||.
Zfish   127 LCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNETCTIMRINRNRCQQCRFKKCLS 191

  Fly    69 VGMSKSGSRYGRRSNWFKIHCLLQEQQTTSGLGGGSSVGSGSGGGVSSASLEQLARLQQA----- 128
            ||||:...|:||...        :|:|                        ..||.:|.|
Zfish   192 VGMSRDAVRFGRIPK--------REKQ------------------------RMLAEMQNAMNNMV 224

  Fly   129 SNQARQTYQDKTNPCIKSATATTSPRIEGAAVGTGIGGGASPSFLQAAKLHHQRQLKLDSRLSNT 193
            :||.:..:|      :.|.|:.|                ..||                   |::
Zfish   225 NNQLQNEFQ------LASITSNT----------------PCPS-------------------SSS 248

  Fly   194 PSDSGASSAGD-PNEDGVTSVLGGQ-------IATPSSTNATSLPKLDLRHPNFPATSEPDADMQ 250
            ||::.:||:.. |   |:|  :|.|       :|...|:.|.:.|.:.|.....|.||.|.....
Zfish   249 PSNTSSSSSSPCP---GLT--VGPQPQPPAVPVAQSPSSPAPTSPTVQLAQSPPPLTSTPPPCTS 308

  Fly   251 RQRHQELLEIFRSHSEPLYSSFAPFSHLPPVLLAAGVPQLPIFKDQFKAEL-------------- 301
            ....:.:..|.|:|.|...     ::|     ...|.|.||     ..:||
Zfish   309 PGVDKTIAAITRAHRETFI-----YAH-----DKLGSPLLP-----HNSELDNRSNNRCMAGYHL 358

  Fly   302 ------------LFPTTSSPELEEPIDLSFRSRADPASPMAHNSNS 335
                        :....::.|:::...|.|::...|.....||:||
Zfish   359 NGHNTIYHHDNNVAHHCNNFEVQQDNSLHFQASQTPEKHQQHNNNS 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eg	NP_524206.1	NR_DBD_like	3..87	CDD:413390	38/82 (46%)
nr1d1	NP_991292.2	NR_DBD_REV_ERB	123..211	CDD:143540	40/115 (35%)
		NR_LBD_REV_ERB	448..635	CDD:132738