Protein Alignment eg and nhr-32

DIOPT Version :10

• Sequence 1: NP_524206.1
• Gene: eg / 40428
• FlyBaseID: FBgn0000560
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: NP_510201.2
• Gene: nhr-32 / 187178
• WormBaseID: WBGene00003626
• Length: 414
• Species: Caenorhabditis elegans
• Alignment Length: 317
• Identity: 73/317 - (23%)
• Similarity: 105/317 - (33%)
• Gaps: 138/317 - (43%)

  Fly     5 CKVCGEPAAGFHFGAFTCEGCKSFFGR--TYNNIAAIAGCKHNGDCVINKKNRTACKACRLRKCL 67
            |.|||:.|.|||:|..:|.||.:||.|  |:|....   |:..|.|.::|..|.||:||||.||.
 Worm    20 CVVCGDAADGFHYGVRSCRGCNAFFRRAVTFNMSFT---CRRGGRCPVDKNARCACRACRLAKCY 81

  Fly    68 LVGMSKSGSRYGRRSNWFKIHCLLQEQQTTSG------------LGGGSSVGSGSGGGVSSASLE 120
            .|||.|...:..|            |..|::|            |||
 Worm    82 AVGMDKKAVQPKR------------EVHTSNGSFDQNDPDYDLRLGG------------------ 116

  Fly   121 QLARLQQASNQARQTYQDKTNPCIKSATATTSPRIEGAAVGTGIGGGASPSFLQAAKLHHQRQLK 185
                             .:|:|..:.::..|||           |...:|..:..|..
 Worm   117 -----------------TRTSPSYELSSDMTSP-----------GSAFTPLNINLADF------- 146

  Fly   186 LDSRLSNTPSDSGASSAGDPNEDGVTSVLGGQI-------------ATPSSTNATSLPKLDLRHP 237
                   ||       |..|:....:|::..|:             ...|.....|..::.|||
 Worm   147 -------TP-------AIPPSPPSDSSLIVRQVYDFMEQKRRRRAMLCGSLEEILSEQEMTLRH- 196

  Fly   238 NFPATSEPDADMQRQRHQELLEIFRSHSEPLYSSFAPFSHLPPVLLAAGVPQLPIFK 294
              |||||           :...||::..               ||:...|.:||.|:
 Worm   197 --PATSE-----------DFTTIFQAQM---------------VLMFEWVEKLPEFR 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eg	NP_524206.1	NR_DBD_like	3..87	CDD:413390	35/83 (42%)
nhr-32	NP_510201.2	NR_DBD_HNF4A	20..95	CDD:143518	35/89 (39%)
		NR_LBD	201..382	CDD:132726	9/51 (18%)