DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syn1 and Magix

DIOPT Version :9

Sequence 1:	NP_001262192.1	Gene:	Syn1 / 40424	FlyBaseID:	FBgn0037130	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_061302.2	Gene:	Magix / 54634	MGIID:	1859644	Length:	324	Species:	Mus musculus

Alignment Length:	156	Identity:	41/156 - (26%)
Similarity:	70/156 - (44%)	Gaps:	22/156 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 GLGISIKGGR--ENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAVRALKRSG 236
            |.|:::.|||  ....|:.:..:.:...|.:...|..||.:|.:||:..:..||.:.|..::..|
Mouse   137 GFGLTLSGGRNVSGDAPLTVHGLLKDGPAQRCGRLQAGDLVLYINGQSTQGLTHAQVVERIRTGG 201

  Fly   237 RVVDLEVKFLREVTPYFRKASIISEVGW--ELQRAFLCPLGPGVPT----SP----PAPKTTPRA 291
            ..:.|.::     .|.....|.|.|||.  :..|: |.|.|..|.:    ||    |..:|:||.
Mouse   202 PHLCLVLQ-----RPQDMDGSRIKEVGGHRKTDRS-LDPRGSRVESRSTISPVHHRPKTRTSPRP 260

  Fly   292 DTRYIPLQLTHLARNLKY--IDPENR 315
            ....:  .:.|:.|.:::  .|.|||
Mouse   261 SPEAV--AIGHVVRAVEHPTEDLENR 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	18/71 (25%)
		PHsplit_syntrophin	<293..351	CDD:269960	6/25 (24%)
Magix	NP_061302.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		PDZ	126..211	CDD:214570	18/78 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	216..263		16/47 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910