DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syn1 and Patj

DIOPT Version :9

Sequence 1:	NP_001262192.1	Gene:	Syn1 / 40424	FlyBaseID:	FBgn0037130	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster

Alignment Length:	135	Identity:	47/135 - (34%)
Similarity:	70/135 - (51%)	Gaps:	23/135 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 IKSDNNGLGISIKG---GRENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAV 229
            :|.|.|||||:|.|   .:|....|.:..:..|.|||.:..:.|.|.|:.|:|:.|:..::.:||
  Fly   321 LKKDANGLGITIAGYVCEKEELSGIFVKSVSPGSAADLSGRIRVNDRIIEVDGQSLQGYSNHQAV 385

  Fly   230 RALKRSGRVVDLEV-KFLREVTPYFRKASIISEVGWELQRAF-----LCPLGPGVPTSPPAPKTT 288
            ..||:||:||:|.: ::||  .|.|.          :||:|.     |....||.|:..|.|  |
  Fly   386 ELLKKSGQVVNLRLERYLR--GPKFE----------QLQQAIAANDKLPSSAPGTPSRAPMP--T 436

  Fly   289 PRADT 293
            |.|.|
  Fly   437 PVATT 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	30/79 (38%)
		PHsplit_syntrophin	<293..351	CDD:269960	1/1 (100%)
Patj	NP_477342.1	L27	12..70	CDD:295425
		PDZ_signaling	154..226	CDD:238492
		PDZ_signaling	318..400	CDD:238492	30/78 (38%)
		PDZ_signaling	557..643	CDD:238492
		PDZ_signaling	726..807	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900