DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syn1 and CG15617

DIOPT Version :9

Sequence 1:	NP_001262192.1	Gene:	Syn1 / 40424	FlyBaseID:	FBgn0037130	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_611151.1	Gene:	CG15617 / 36871	FlyBaseID:	FBgn0034151	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	49/221 - (22%)
Similarity:	82/221 - (37%)	Gaps:	47/221 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 DVPDHVANQKRHVRIIKSDNNGL-------GISIKGGRENRMPILISKIF-RGMAADQAKGLYVG 209
            |..|:||.:.:....:::|...:       |:.:.||.:...|:.|..:. .|:|  :..|:.||
  Fly    14 DAFDNVAYELQMTYTLETDCRIMSFYDAMWGMEVTGGIDQFEPLTIVNVSPTGLA--KRGGMRVG 76

  Fly   210 DAILTVNGEELRDATHDEAVRALKRSGRVVDLEVKFLREVTPYFRKASIISEVGWELQRAFLCPL 274
            |.|..:|.....:.|.:||::..:::.|.|.:.|:...:..         .|..|... .:..|.
  Fly    77 DEITQINDVPALEMTFNEALQMFRKNSRYVRVYVRGDDDAP---------GEEDWTCD-CWFKPR 131

  Fly   275 GPGVPTSPPAPKTTPRADTRYIPLQLTHLARNLKYIDPENRCFELHSPDGVHSCILRAADSAEAL 339
            .|......|...|.|..|.|             |.:..|:.||.:.|.........|||.|
  Fly   132 KPWRRDFTPIQWTFPWNDRR-------------KPVYKESNCFMVPSKMEEKIRARRAATS---- 179

  Fly   340 VWFNALHSAMGTSTQRALAEANRALT 365
                |:|.      :..||...|:||
  Fly   180 ----AVHK------KDELAPHTRSLT 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	19/88 (22%)
		PHsplit_syntrophin	<293..351	CDD:269960	12/57 (21%)
CG15617	NP_611151.1	PDZ_signaling	30..111	CDD:238492	19/82 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900