Protein Alignment Syn1 and AgaP_AGAP007108

DIOPT Version :9

• Sequence 1: NP_001262192.1
• Gene: Syn1 / 40424
• FlyBaseID: FBgn0037130
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: XP_308649.4
• Gene: AgaP_AGAP007108 / 1269994
• VectorBaseID: AGAP007108
• Length: 879
• Species: Anopheles gambiae
• Alignment Length: 458
• Identity: 106/458 - (23%)
• Similarity: 155/458 - (33%)
• Gaps: 147/458 - (32%)

  Fly    11 PPAAQQPIPQQHSPSPSGLRCGNMETRVRGA----WYRVLVTLETDFLAVSLDESCEAAQPSNDG 71
            |.||..|........|        ||.|.|.    |.|:|     |...|            |||
Mosquito   119 PAAATGPFTDSPKSVP--------ETIVAGTGPADWSRIL-----DIELV------------NDG 158

  Fly    72 QSTTLN-GTLGSNHSG-------GGGGGAGGGGTGGGGQ-----NGTLPNSASLQ--------GM 115
              |.|. |.:|:..:|       .||.....|....|.|     :..|....|.|        |.
Mosquito   159 --TGLGFGIIGARTTGVTVKTILAGGVADRDGRLKSGDQILQIGDVNLHEMVSEQVASVLRQSGT 221

  Fly   116 NIQ-------DTELDGSASNDNGDRDPC------LNNNNNAGDGGGMDMCDV------------- 154
            ::|       |....|:...|:....|.      |.......|.|..|:..|
Mosquito   222 HVQLVVARPIDPATVGTDEYDHSAIVPTVLLANPLKLKQYLSDSGFGDIYSVYSIANLDSPGLEN 286

  Fly   155 --------PDHVANQKRHVRIIKSDNNGLGISIKG---GRENRMPILISKIFRGMAADQAKGLYV 208
                    ||....:...|. ::.|.|||||:|.|   .:|....|.:..:..|.|||.:..:.|
Mosquito   287 PFRQESPLPDFPETEVFTVE-LRKDQNGLGITIAGYVCEKEELSGIFVKSVSPGSAADLSGKIQV 350

  Fly   209 GDAILTVNGEELRDATHDEAVRALKRSGRVVDLEV-KFLREVTPYFRKASIISEVGWELQRAFLC 272
            .|.|:.|:|:.|...::.:||..||:||.||.|.: ::||  .|.:.          :||:|...
Mosquito   351 NDRIIEVDGQSLHGFSNHQAVDVLKQSGHVVTLCLERYLR--GPKYD----------QLQQAIAA 403

  Fly   273 -PLGPGVPTSPPAPKTTPRADTRYIPLQLTHLARNLKYI-------------------DPENRCF 317
             .:.|..|.:||.|         .:|..|:....|:..|                   :|:::..
Mosquito   404 NEMKPPTPATPPPP---------LVPTDLSKYGSNILDILPPQALQRTLGLEQEQAAGEPDDQLA 459

  Fly   318 E----------LHSPDGVHSCILRAADSAEALVWFNALHSAMGTSTQRALAEANRAL--TNLIGE 370
            |          ||.  |.|..:.||.||.:...:.:.:..|. .....|:||....|  ||.:..
Mosquito   460 ECDVAGLDGGPLHM--GGHKKLSRAKDSIDTQEYRDKIKEAT-IVPDGAVAEDGTLLDATNPVAI 521

  Fly   371 LKH 373
            .:|
Mosquito   522 ARH 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622	9/34 (26%)
		PDZ_signaling	163..244	CDD:238492	30/84 (36%)
		PHsplit_syntrophin	<293..351	CDD:269960	15/86 (17%)
AgaP_AGAP007108	XP_308649.4	PDZ_signaling	149..228	CDD:238492	21/97 (22%)
		PDZ_signaling	302..383	CDD:238492	29/81 (36%)
		PDZ_signaling	576..652	CDD:238492
		PDZ	749..838	CDD:214570

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900