Protein Alignment Syn1 and Patj

DIOPT Version :9

• Sequence 1: NP_001262192.1
• Gene: Syn1 / 40424
• FlyBaseID: FBgn0037130
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_766284.2
• Gene: Patj / 12695
• MGIID: 1277960
• Length: 1834
• Species: Mus musculus
• Alignment Length: 462
• Identity: 108/462 - (23%)
• Similarity: 169/462 - (36%)
• Gaps: 116/462 - (25%)

  Fly    14 AQQPIPQ-QHSPSP----SGLRCGNMETRVRGAWYRVLVTLETDFLAVSLDESCEAAQPSNDGQS 73
            |..|.|: .|||||    .|....:.|.             |:...|..|.|. |:::|.:..|.
Mouse  1335 AVAPFPELSHSPSPVEDLGGTELVSSEE-------------ESSVDAKHLPEP-ESSKPEDLSQV 1385

  Fly    74 TTLNGTLGSNHSGGGGGGAGGGGTGGGGQNGTLPNSASLQ-GMNIQDTELDGSASNDNGDRDPCL 137
            ...|......                  :....|:||:.| ......|::..|:.:......|..
Mouse  1386 VDDNMVAEQQ------------------KESESPDSAACQIKQQTYSTQVSSSSQDSPSSPAPLC 1432

  Fly   138 NNNNNAGDGGGMDMCDVP-------------DHVANQKRHVRIIKSDNNGLGISIKGGRENRM-P 188
            .:.:....|.|.....:|             ..|..|:..:.|.|. .:|||:||.||::..: .
Mouse  1433 QSAHADVTGSGNFQAPLPVDPAPLSVDPATCPIVPGQEMIIEISKG-RSGLGLSIVGGKDTPLDA 1496

  Fly   189 ILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAVRALKRSGRVVDLEVKFLREVTPYF 253
            |:|.:::...||.:...|:.||.||.|||.:||.::|:||:.||:::.:.|.|.|        |.
Mouse  1497 IVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRSSSHEEAITALRQTPQKVRLVV--------YR 1553

  Fly   254 RKASIISEVGWELQRAFLCPLGPGVPTSPPAPKTTPRADTRYIPLQLTHLARNLKYIDPENRCFE 318
            .:|....|...|:   ||..|          .|.|.|.      |.|:.:.:
Mouse  1554 DEAQYRDEENLEV---FLVDL----------QKKTGRG------LGLSIVGK------------- 1586

  Fly   319 LHSPDGVH-SCILR--AADSAEALVWFNALHSAMGT----STQRALAEANRALTNL----IGELK 372
             .|..||. |.|::  |||....|:..:.:.|..|.    ::|..:|...:.:..|    ||.|:
Mouse  1587 -RSGSGVFISDIVKGGAADLDGRLIRGDQILSVNGEDMRHASQETVATILKCVQGLVQLEIGRLR 1650

  Fly   373 HIGWLSKRMSGGGSSGSAGGGAASGGSGTSNSVVAGELVSPSGRSSSESSDESDKWLPIFVAVTE 437
            ...|.:.|.:...|.|..  .:|......|.:.|...|.:..|  :..|||...|       .||
Mouse  1651 AGSWAASRKTSQNSQGDQ--HSAHSSCRPSFAPVITSLQNLVG--TKRSSDPPQK-------CTE 1704

  Fly   438 REFRIYE 444
            .|.|..|
Mouse  1705 EEPRTVE 1711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622	4/30 (13%)
		PDZ_signaling	163..244	CDD:238492	30/81 (37%)
		PHsplit_syntrophin	<293..351	CDD:269960	12/60 (20%)
Patj	NP_766284.2	L27_2	8..65	CDD:312549
		PDZ_signaling	135..218	CDD:238492
		PDZ_signaling	248..325	CDD:238492
		PDZ_signaling	363..450	CDD:238492
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	456..488
		PDZ_signaling	572..636	CDD:238492
		PDZ	685..774	CDD:214570
		PDZ_signaling	1072..1163	CDD:238492
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1171..1219
		PDZ	1242..1327	CDD:214570
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1340..1453		26/144 (18%)
		MPDZ_u10	<1453..1468	CDD:374710	1/14 (7%)
		PDZ	1469..1554	CDD:214570	33/93 (35%)
		PDZ_signaling	1566..1646	CDD:238492	22/112 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1657..1676		4/20 (20%)
		PDZ_signaling	1707..1792	CDD:238492	2/5 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1811..1834

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810