DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Als2 and JPH2

Sequence 1:NP_649347.1 Gene:Als2 FlyBaseID:FBgn0037116 Length:1486 Species:Drosophila melanogaster
Sequence 2:NP_065166.2 Gene:JPH2 HGNCID:14202 Length:696 Species:Homo sapiens

Alignment Length:288 Identity:76/289 (26%)
Similarity:111/289 (38%) Gaps:55/289 (19%)


  Fly   759 EYPDGSVYCGELQHGIIEGFGKMVIPT-TGLYVGNFKGGRFHGHGVYEMHCKDSPESEVYEGNFC 822
            ::.||..|||..:.|...|.|....|. .|.|.|::..| |...|||..     |....:||.:.
Human     7 DFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFG-FEVAGVYTW-----PSGNTFEGYWS 65

  Fly   823 EGLFHGHGVMRNNRYIYVGEYQANARSGYGVIEDLVSGDKYMGMFADNKRSGIGSCITNRGDYFE 887
            :|..||.|:....|::|.||:....:..||:.:...||.||.|.:.:..:.|.|:.....|..::
Human    66 QGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQ 130

  Fly   888 GSFSGDDLTGSGVAVFENDYYYEGELTLLGP-------------NGRGEYYMPSGDACGG----S 935
            |.|:.....|.||   .....|...:.:..|             ||......|:..|..|    |
Human   131 GQFTNGMRHGYGV---RQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPASDGPALPS 192

  Fly   936 GAMGTGEFDDTCELIGN-------KMFGQLSGTWDTVRIQAGELVLNRRFPKYPSSLGRQVVDHN 993
            .|:..|.|  ...|:.|       ...|.|        .|.|.|:...|..:..:|:|.|     
Human   193 PAIPRGGF--ALSLLANAEAAARAPKGGGL--------FQRGALLGKLRRAESRTSVGSQ----- 242

  Fly   994 RKWRSLFNNFESDL---ANCTASTSSSG 1018
               ||..:..:|||   |:..|||:|.|
Human   243 ---RSRVSFLKSDLSSGASDAASTASLG 267

Known Domains:


GeneSequenceDomainRegion External IDIdentity
Als2NP_649347.1 RCC1 258..304 CDD:278826
RCC1_2 292..321 CDD:290274
RCC1 308..361 CDD:278826
PH-like 616..715 CDD:302622
VPS9 1373..1479 CDD:280383
JPH2NP_065166.2 MORN 1. {ECO:0000255} 14..36 7/22 (32%)
MORN 2. {ECO:0000255} 38..59 8/27 (30%)
MORN 3. {ECO:0000255} 60..79 6/19 (32%)
MORN 4. {ECO:0000255} 82..104 7/22 (32%)
MORN 106..128 CDD:280628 5/22 (23%)
MORN 5. {ECO:0000255} 106..128 5/22 (23%)
MORN 6. {ECO:0000255} 129..151 6/25 (24%)
MORN 7. {ECO:0000255} 291..313
MORN 314..336 CDD:280628
MORN 8. {ECO:0000255} 314..336
Bipartite nuclear localization signal. {ECO:0000250|UniProtKB:Q9ET78} 351..365
Nuclear localization signal. {ECO:0000250|UniProtKB:Q9ET78} 495..499
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_COG4642
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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