DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Als2 and Morn4

DIOPT Version :9

Sequence 1:	NP_649347.1	Gene:	Als2 / 40410	FlyBaseID:	FBgn0037116	Length:	1486	Species:	Drosophila melanogaster
Sequence 2:	NP_001020146.1	Gene:	Morn4 / 293950	RGDID:	1307336	Length:	146	Species:	Rattus norvegicus

Alignment Length:	116	Identity:	38/116 - (32%)
Similarity:	60/116 - (51%)	Gaps:	9/116 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   760 YPDGSVYCGELQHGIIEGFGKMVIPTTGLYVGNFKGGRFHGHGVYEMHCKDSPESEVYEGNFCEG 824
            |..|..|.||.:.|...|||:::....|.|:|:|:.|.|:|.||...     .:...|||.|.:|
  Rat    10 YSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTF-----SDGSRYEGEFSQG 69

  Fly   825 LFHGHGV-MRNNRYIYVGEYQANARSGYGVI--EDLVSG-DKYMGMFADNK 871
            .|:|.|| :|.:...:.||::.....|:|::  .|...| .:..|:|.:||
  Rat    70 KFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGLPRNEGLFENNK 120

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	RCC1	258..304	CDD:278826
		RCC1_2	292..321	CDD:290274
		RCC1	308..361	CDD:278826
		PH-like	616..715	CDD:302622
		VPS9	1373..1479	CDD:280383
Morn4	NP_001020146.1	COG4642	5..106	CDD:226989	33/100 (33%)
		MORN 1	16..38		7/21 (33%)
		MORN 2	39..61		8/26 (31%)
		MORN 3	62..84		10/21 (48%)
		MORN 4	85..107		5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900