Protein Alignment TfAP-2 and tfap2a

DIOPT Version :10

• Sequence 1: NP_001262178.1
• Gene: TfAP-2 / 40398
• FlyBaseID: FBgn0261953
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: XP_012819931.1
• Gene: tfap2a / 395064
• XenbaseID: XB-GENE-481201
• Length: 471
• Species: Xenopus tropicalis
• Alignment Length: 486
• Identity: 212/486 - (43%)
• Similarity: 279/486 - (57%)
• Gaps: 86/486 - (17%)

  Fly     6 RTNDHQFEDQKFMMERLSGHGSLGLSSGSAAYTTHSGGHTGRSGPATGHSGHSSTHGSAATMHHQ 70
            ||:|.......:..:....|.  |.|:|:|..            |..|..| .|.:.||..:.|
 Frog    36 RTSDMDMSFPGYSQDSQDRHD--GTSNGTARL------------PQLGTVG-QSPYASAPPLSH- 84

  Fly    71 SLQSDFQPPYFPPPFHHSTQSPPQQQISGYLQNHGALEYLGTDPYGQPLSSLHHAPLHHYNQLAG 135
            :..:||||||||||:         |.|  |.|:.....:: .|||.  |::||..|...:....|
 Frog    85 TPNADFQPPYFPPPY---------QPI--YPQSQDPYSHV-NDPYS--LNALHTQPQPQHPGWPG 135

  Fly   136 LRSTQDQLGIHRTHREAELQGHVTQLSHGFPY----TDRRSDY---------GSAISAGAAHGTR 187
            .|.:|:...:| |||             |.|:    .|.|.||         ...:|:|
 Frog   136 QRQSQETSLLH-THR-------------GIPHQLSGLDPRRDYRRHEDLLHGPHGLSSG------ 180

  Fly   188 LGHEHESLALHQALQNAVDDV---QAPAL---DDNVAFMSDLPLIKSMKSGKEA-----GNIGSG 241
            ||    .|.|| ::.:.::||   :.|::   |..|.....:.|.||..:...:     .|:..|
 Frog   181 LG----DLPLH-SIPHGIEDVSHIEDPSINIPDQTVIKKGPVSLSKSNNNAVSSLSLNKDNLFGG 240

  Fly   242 --SPSEVFCAVPGRLSLLSSTSKYKVTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREK 304
              :|:||||:|||||||||||||||||:||||||||||||||||||||||||||||||||.||||
 Frog   241 VVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREK 305

  Fly   305 LEKIGLNLPAGRRKAANVTLLTSLVEGEATHLAKDFHFVCETEFPARQLAEYIVRHQTEPQDSYR 369
            |:|||||||||||||||||||||||||||.|||:||.:||||||||:.:.||:.|..::|.:...
 Frog   306 LDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAIGEYVNRQHSDPNEQVT 370

  Fly   370 RKELILHSQQITKELMQILSQDRTTHFGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAF 434
            ||.::|.::||.||...:|||||:....:|...:|||.:|..||||:||:|||||||:.|.:.|.
 Frog   371 RKNMLLATKQICKEFTDLLSQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAITAL 435

  Fly   435 QTFLNESLNYLEKLYPSNGGGMVSSSLDKSK 465
            |.:|.|:|..::|:|.:|     :|..|.||
 Frog   436 QNYLTEALKAMDKMYLNN-----NSHTDNSK 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:460877	134/193 (69%)
tfap2a	XP_012819931.1	TF_AP-2	248..442	CDD:460877	134/193 (69%)