Protein Alignment TfAP-2 and Tfap2e

DIOPT Version :10

• Sequence 1: NP_001262178.1
• Gene: TfAP-2 / 40398
• FlyBaseID: FBgn0261953
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001178693.1
• Gene: Tfap2e / 313596
• RGDID: 1563297
• Length: 442
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 217/479 - (45%)
• Similarity: 265/479 - (55%)
• Gaps: 105/479 - (21%)

  Fly    19 MERLSG----HGSLGLSS-GSAAYTTHSGGHTGRSGPATGHSGHSSTHGSAATMHHQSLQSDFQP 78
            |||..|    .|...||| ..|||           |||.     ...|..||     |..:|:.|
  Rat     9 MERPDGLCAAAGGTRLSSLPQAAY-----------GPAP-----PLCHTPAA-----SATTDYHP 52

  Fly    79 PYFPPPFHHSTQSPPQQQISGYLQN---HGALEYLGTDPYG--------QPLSSLHHAP---LHH 129
            ||||||:       ||.|:. |.|.   ..|..:|..||||        ||..:...||   ...
  Rat    53 PYFPPPY-------PQAQLP-YGQGPDAAAAFPHLAPDPYGGLAPLAQPQPPQAAWAAPRAAARA 109

  Fly   130 YNQLAGLRSTQDQ-LGIHRTHREAELQGHVTQLSHGFPYTDRRSDYGSAIS------AGAAHG-- 185
            :::..||.:...: ||:                       |.|.||.:|:.      |..|||
  Rat   110 HDEPPGLLAPPARALGL-----------------------DPRRDYAAAVPRLLHSLADGAHGLA 151

  Fly   186 -TRLGHEHESLALHQALQ--NAVDDVQAPALDDNVAFMSDLPLIKSMKSGKEAGNI--------- 238
             ..||  ...||....|:  .|:||.....||.:|        ||.:....:||::
  Rat   152 DAPLG--LPGLAAPPGLEELQAIDDPGMSLLDQSV--------IKKVPVPSKAGSLSTLSLSKDS 206

  Fly   239 ---GSGSPSEVFCAVPGRLSLLSSTSKYKVTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRL 300
               |..:||||||:|||||||||||||||||:.|||||||||||||||||||||||||||||||.
  Rat   207 LVGGINNPSEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRC 271

  Fly   301 LREKLEKIGLNLPAGRRKAANVTLLTSLVEGEATHLAKDFHFVCETEFPARQLAEYIVRHQTEPQ 365
            |||:|||||||||||||||||||||||||||||.|||:||.:||||||||:..|||:.|...:|.
  Rat   272 LRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLGRQHADPG 336

  Fly   366 DSYRRKELILHSQQITKELMQILSQDRTTHFGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAV 430
            :.:.||.::|.::||.||...:::|||:....:|...:|||.:|..||||||||||||.|||.|.
  Rat   337 ELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAA 401

  Fly   431 LHAFQTFLNESLNYLEKLYPSNGG 454
            |.|||.:|.|||..|:|::.|:.|
  Rat   402 LTAFQNYLLESLKGLDKMFLSSAG 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:460877	136/193 (70%)
Tfap2e	NP_001178693.1	TF_AP-2	218..412	CDD:460877	136/193 (70%)