Protein Alignment TfAP-2 and Tfap2a

DIOPT Version :10

• Sequence 1: NP_001262178.1
• Gene: TfAP-2 / 40398
• FlyBaseID: FBgn0261953
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: XP_030103084.1
• Gene: Tfap2a / 21418
• MGIID: 104671
• Length: 482
• Species: Mus musculus
• Alignment Length: 483
• Identity: 216/483 - (44%)
• Similarity: 279/483 - (57%)
• Gaps: 73/483 - (15%)

  Fly    31 SSGSAAYTTHSGGHTGR--SGPATG----------HSGHS--------------STHGSAATMHH 69
            ::||.:...:|.|...|  ..||.|          |.|.|              |.:.||..:.|
Mouse    28 AAGSTSQAQNSVGSRQRVPGAPARGARPPLHPEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSH 92

  Fly    70 QSLQSDFQPPYFPPPFHHSTQSPPQQQISGYLQNHGALEYLGTDPYGQPLSSLHHAPLHHYNQLA 134
             :..:||||||||||:         |.|  |.|:.....:: .|||.  |:.||..|...:....
Mouse    93 -TPNADFQPPYFPPPY---------QPI--YPQSQDPYSHV-NDPYS--LNPLHAQPQPQHPGWP 142

  Fly   135 GLRSTQDQLGIHRTHREAELQGHVTQLSHGFPYTDRRSDYGSAISAGAAHGTR-LGHEHESLALH 198
            |.|.:|:. |:..|||         .|.|.....|.|.||..  .....||.. ||.....|.:|
Mouse   143 GQRQSQES-GLLHTHR---------GLPHQLSGLDPRRDYRR--HEDLLHGPHGLGSGLGDLPIH 195

  Fly   199 QALQNAVDDVQAPALDDNVAFMSDLPLIKS-----MKSGKEA--------GNIGSG--SPSEVFC 248
             :|.:|::||  |.::|....:.|..:||.     .||...|        .|:..|  :|:||||
Mouse   196 -SLPHAIEDV--PHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFC 257

  Fly   249 AVPGRLSLLSSTSKYKVTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLP 313
            :|||||||||||||||||:||||||||||||||||||||||||||||||||.|||||:|||||||
Mouse   258 SVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLP 322

  Fly   314 AGRRKAANVTLLTSLVEGEATHLAKDFHFVCETEFPARQLAEYIVRHQTEPQDSYRRKELILHSQ 378
            ||||||||||||||||||||.|||:||.:||||||||:.:||::.|..::|.:...||.::|.::
Mouse   323 AGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVARKNMLLATK 387

  Fly   379 QITKELMQILSQDRTTHFGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAFQTFLNESLN 443
            ||.||...:|:|||:....:|...:|||.:|..||||:||:|||||||:.|.:.|.|.:|.|:|.
Mouse   388 QICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALK 452

  Fly   444 YLEKLYPSNGGGMVSSSLDKSKIDNEKK 471
            .::|:|.||.....:.:..||. |.|:|
Mouse   453 AMDKMYLSNNPNSHTDNSAKSS-DKEEK 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:460877	133/193 (69%)
Tfap2a	XP_030103084.1	TF_AP-2	256..450	CDD:460877	133/193 (69%)