Protein Alignment TfAP-2 and tfap2a

DIOPT Version :10

• Sequence 1: NP_001262178.1
• Gene: TfAP-2 / 40398
• FlyBaseID: FBgn0261953
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: XP_005162615.1
• Gene: tfap2a / 140618
• ZFINID: ZDB-GENE-011212-6
• Length: 457
• Species: Danio rerio
• Alignment Length: 446
• Identity: 205/446 - (45%)
• Similarity: 273/446 - (61%)
• Gaps: 50/446 - (11%)

  Fly    40 HSGGHTGRSG-PATGHSGHSSTHGSAATMHHQSLQSDFQPPYFPPPFHHSTQSPPQQQISGYLQN 103
            |.|...|.:. |..|..| .|.:.||..:.| :..|||||||||||:         |.|  |.|:
Zfish    44 HDGTSNGTARLPQLGSVG-QSPYTSAPPLSH-TPNSDFQPPYFPPPY---------QPI--YPQS 95

  Fly   104 HGALEYLGTDPYGQPLSSLHHAPLHHYNQLAGLRSTQDQLGIHRTHREAELQGHVTQLSHGFPYT 168
            .....:: .|||.  ::|||......:....|.|.:|:...:|: ||             |.|:.
Zfish    96 QDPYSHV-NDPYS--INSLHAQSQPQHPGWPGQRQSQESSLLHQ-HR-------------GLPHQ 143

  Fly   169 DRRSDYGSAISAGAAHGTRLGHEHESLALHQALQNAVDDVQAPALDDNVAFMSDLPLIKS--MKS 231
            ..| :|...:...:.||...|.. :|:.:| .:.::::|||  .::|....:.|..:||.  :..
Zfish   144 LCR-EYRREVLLPSGHGIDTGLT-DSIPIH-GIPHSLEDVQ--QVEDQGIHIPDQTVIKKGPVSI 203

  Fly   232 GKEAGNI------------GSGSPSEVFCAVPGRLSLLSSTSKYKVTIAEVQRRLSPPECLNASL 284
            .|...||            |..:|:||||:|||||||||||||||||:|||||||||||||||||
Zfish   204 SKNNSNISAIPINKDGLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASL 268

  Fly   285 LGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEGEATHLAKDFHFVCETEFP 349
            |||||||||||||||.|||||:|||||||||||||||||||||||||||.|||:||.:|||||||
Zfish   269 LGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFP 333

  Fly   350 ARQLAEYIVRHQTEPQDSYRRKELILHSQQITKELMQILSQDRTTHFGTRSQHLLEPSMQRHLTH 414
            |:.:|||:.|..::|.:..:||.::|.::||.||...:|||||:....:|.|.:|||.:|..|||
Zfish   334 AKAIAEYMNRQHSDPNEQVQRKNMLLATKQICKEFTDLLSQDRSPLGNSRPQPILEPGIQSCLTH 398

  Fly   415 FSLITHGFGSPAIMAVLHAFQTFLNESLNYLEKLYPSNGGGMVSSSLDKSKIDNEK 470
            ||||:||||:||:.|.|.|.|.:|.|::..::|:|.:|.....|.:..|:...:||
Zfish   399 FSLISHGFGTPAVCAALTALQNYLTEAIKAMDKMYLNNNPNSHSETGSKAGDKDEK 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:460877	137/193 (71%)
tfap2a	XP_005162615.1	TF_AP-2	231..425	CDD:460877	137/193 (71%)