Protein Alignment Alp1 and Alpi

DIOPT Version :10

• Sequence 1: NP_001262159.1
• Gene: Alp1 / 40372
• FlyBaseID: FBgn0283479
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001074551.1
• Gene: Alpi / 76768
• MGIID: 1924018
• Length: 554
• Species: Mus musculus
• Alignment Length: 506
• Identity: 223/506 - (44%)
• Similarity: 290/506 - (57%)
• Gaps: 35/506 - (6%)

  Fly    35 SELKSKEFWFHDAQRTLYNKLSTPPNQYRAKNVIFFLGDGMSVPTVTAGRIFDGQLRGVVGERNR 99
            :|.::..||...|...|.......|.|..|||:|.||||||.||||||.||..|||.|.:|....
Mouse    24 AEEENPAFWNKKAAEALDAAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPETP 88

  Fly   100 LEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKANYLTIGVTADVELNDCRGSRLPQNRLSS 164
            |..:.|.|:.|||||.|::||.|||.||:|||.|:||||.|||::|...|:.|..:.  .|.:.|
Mouse    89 LAMDLFPYMALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGLSAAARLDQCNTTF--GNEVFS 151

  Fly   165 IAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDVTKLGQNPGNCPDIAQQLIDG-D 228
            :...|.|..||.|:||||||.||||||.||||.||::.||.::.......| |.|||.|||.. |
Mouse   152 VMYRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDAEMPASALQDG-CKDIATQLISNMD 215

  Fly   229 VGKRLRVVMGGGTIKFLPNTTNDV-----FGNKGQRLDNRNLIEEWQQTKPGNARVVFSRTDLL- 287
            :.    |::|||.....|..|.|.     ....|.|||::||::.|.....| ||.|::|::|:
Mouse   216 ID----VILGGGRKFMFPKGTPDPEYPSDSNQSGTRLDDQNLVQTWLSKHQG-ARYVWNRSELIQ 275

  Fly   288 -NNDAQNTDFLLGLFNASHLAY--HMDDSIDTPTLPEMTAAAINVLSRDPNGYFLFVEGGRIDHA 349
             :.|...| .|:|||..:.:.|  :.:.|:| |:|.|||..|:.:|||:|.|::|||||||||..
Mouse   276 ASQDPAVT-HLMGLFEPTEMKYDANRNPSVD-PSLAEMTEVAVRMLSRNPQGFYLFVEGGRIDQG 338

  Fly   350 HHETKAKKALDETVQFSDAVRKARQLTNPWDTLIVVSADHGHTVTISGYPDVNNSIVGLNSELSN 414
            ||...|..||.|.|.|..|:.||.||||..||||:::|||.|.....||.....||.|| :.|..
Mouse   339 HHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLILITADHSHVFAFGGYTLRGTSIFGL-APLKA 402

  Fly   415 VDQLPYTSISYANGPAYERFYKSTDGVVERVDLRNLDFSKPDAIYPHGVPMTEETHGGGDVAVYA 479
            :|...||||.|.|||.||....:...|.|   .:::|   |:......||::.|||||.|||::|
Mouse   403 LDDKSYTSILYGNGPGYELKSGNRPNVTE---AQSVD---PNYKQQAAVPLSSETHGGEDVAIFA 461

  Fly   480 HVVEYLLQGPWSHLFTGVYEQSTLPHLMGFASCLGPGITYCDLQPKARYSP 530
                   :||.:||..||.||:.:.|:|.||.||.| .|.|.|.|.|..||
Mouse   462 -------RGPQAHLVHGVQEQNYIAHVMAFAGCLEP-YTDCGLAPPAGQSP 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp1	NP_001262159.1	alkPPc	65..514	CDD:214515	206/458 (45%)
Alpi	NP_001074551.1	Alk_phosphatase	53..488	CDD:395188	206/458 (45%)