Protein Alignment AcCoAS and acss1

DIOPT Version :10

• Sequence 1: NP_730611.1
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001074125.3
• Gene: acss1 / 541435
• ZFINID: ZDB-GENE-050320-139
• Length: 693
• Species: Danio rerio
• Alignment Length: 650
• Identity: 310/650 - (47%)
• Similarity: 410/650 - (63%)
• Gaps: 38/650 - (5%)

  Fly    22 SFEEYQKFYQESLDNPAEFWSRVAKQ-FHWETPADQDKFLKYNFNISKGPISIKWMEGASTNLCY 85
            |...|...|:.|:.:|..||..:||: ..|..|.||..    :.:||.|  .|.|..|...|:..
Zfish    58 SGRNYADLYELSVKDPENFWGSIAKERLAWTKPFDQVS----DCDISSG--KINWFLGGQLNVSV 116

  Fly    86 NLLDRNVRNGLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVLKDHGIRKGDRVSIYMPMI 150
            |.||.:|.|. ..::|..||.:.|....| :|||:|||..||.||.||.||:::|:||:||||:.
Zfish   117 NCLDVHVAND-PSRVALIWEKDEPGTEER-ITYRELLEMTCRLANTLKSHGVQRGERVAIYMPVS 179

  Fly   151 LELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAWRGEKPLYLKALCDTALE 215
            .....||||||||||||::||||||.::||.|:.|.:.|.:||.:...||.:...||:..|.|
Zfish   180 PMAVAAMLACARIGAVHTVVFAGFSSEALAGRIQDAQCKFVITCNQGVRGGRVFDLKSTVDKA-- 242

  Fly   216 KVEEMGHSVEKCIVVSHL---KRVTPCQPDHVEEEIPWTDDRDYWWHEEMEDKEPACYPEWMDAE 277
                    |:.|..|.|:   ||.....| ..:.:||        ..|.|..:...|.||.|::|
Zfish   243 --------VKSCPSVRHVFVAKRTNNSVP-MGKLDIP--------LEEVMAGQSSECAPEPMESE 290

  Fly   278 DPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDIYWCTGDVGWITGHTYVVYGPL 342
            :.|||||||||||||||::||.|||||||:.|.:.||||.|||::.|..|:||||||:|||||||
Zfish   291 EMLFMLYTSGSTGKPKGIVHTQAGYLLYASLTHQYVFDYTPGDVFGCVADIGWITGHSYVVYGPL 355

  Fly   343 ANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALMKFGEGPVLKHNLSGLKVLGSV 407
            .||||||:||.||.:|...|||..:.:.::.|||.||||||.|:|:.|..|.|::.|.||.|.||
Zfish   356 CNGATSVLFESTPVYPNPGRYWETVQRLRINQFYGAPTAIRLLLKYEESWVKKYDRSSLKTLASV 420

  Fly   408 GEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGATP---MKPGSASFPFFGVKPTL 469
            |||||.|||.|::..:|..:|.:|||:|||||||..|.||| |.|   ::|..|..||||:||.|
Zfish   421 GEPINHEAWDWFHNVVGDGRCPLVDTWWQTETGGVCIAPLP-AEPGAEIRPAMAMRPFFGIKPEL 484

  Fly   470 LDECGIEIKG-EGEGYLVFSQPWPGMMRTLYNNHERFEDTYFSKFPGYYCTGDGARRDADGYLWI 533
            |.|.|..|.| :..|.|..|||||||.||::.:|:||.|.||..:.|.|.|||||.|..|||..|
Zfish   485 LGEKGQIITGNDVNGALCISQPWPGMARTIFGDHQRFVDAYFKPYQGQYFTGDGAYRTEDGYYQI 549

  Fly   534 TGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCFITPNENEVFDQK-LI 597
            |||:||::|:|||.:.|||:|..|.|||.|.|:||:..||.:|||..:.|:...|:...:|: ::
Zfish   550 TGRMDDVINISGHRLGTAEIEDALDEHPDVPETAVIGIPHEIKGEVPFAFVVLKESAAENQQAVV 614

  Fly   598 SDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLRKIAVND-RNVGDTSTLADEQIVEQL 661
            ::|:.:|..:|..:|:||.......||||||||||||:|||:||.| .|:||.|||.|..:|.::
Zfish   615 NELRHLVASKIAKYAVPDHFLVVKRLPKTRSGKIMRRILRKVAVQDTSNLGDVSTLDDPSVVSEI 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_730611.1	ACS	24..654	CDD:341270	307/639 (48%)
acss1	NP_001074125.3	ACS	62..672	CDD:341270	307/637 (48%)