Protein Alignment AcCoAS and acss2

DIOPT Version :10

• Sequence 1: NP_730611.1
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001315282.1
• Gene: acss2 / 436914
• ZFINID: ZDB-GENE-040718-388
• Length: 698
• Species: Danio rerio
• Alignment Length: 678
• Identity: 420/678 - (61%)
• Similarity: 518/678 - (76%)
• Gaps: 28/678 - (4%)

  Fly    14 ISQNAYISSFEEYQKFYQESLDNPAEFWSRVAKQFHWETPADQDKFLKYNFNISKGPISIKWMEG 78
            :.:.|:|.|||:|::.|.:|:::|.|||:.|||.|.|:|.. ..|||.|||:::||.|.||.|||
Zfish    18 LKKEAHIPSFEKYKELYIKSVESPEEFWADVAKDFFWKTKY-TGKFLDYNFDVTKGEIYIKCMEG 81

  Fly    79 ASTNLCYNLLDRNV-RNGLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVLKDHGIRKGDR 142
            |:||:|||:||||| ...|||::|:|||||.|.| .:.:|||:||::||:||||||..|::||||
Zfish    82 ATTNICYNVLDRNVHERKLGDRVAFYWEGNEPGD-EKTVTYRELLQQVCKFANVLKSQGVKKGDR 145

  Fly   143 VSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAWRGEKPLYLK 207
            |||||||::||.:||||||||||||||||||||.:||.||:.|.:..|||||||.:||:|.:.||
Zfish   146 VSIYMPMVVELVVAMLACARIGAVHSIVFAGFSSESLCERIMDSQCCLLITADGFYRGDKLINLK 210

  Fly   208 ALCDTALEKVEEMGHSVEKCIVVSHL---------------KRVTP-----CQPDHVEE-----E 247
            .:.|.||:|..:....|||||::.||               ||..|     .|.:.|.:     :
Zfish   211 LIADEALKKCRDKSFPVEKCIMLKHLTKEDEASSGSLSPPAKRACPDLQQEKQKERVRKVRPPPQ 275

  Fly   248 IPWTDDRDYWWHEEMEDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKI 312
            :||..:.|..||..:......|.|.|.|:|||||:||||||||||||||||.:||:||.|:|||:
Zfish   276 VPWNPEVDMCWHSLIGGASEECEPVWCDSEDPLFILYTSGSTGKPKGVLHTVSGYMLYTASTFKM 340

  Fly   313 VFDYKPGDIYWCTGDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYT 377
            ||||...|:||||.|:||||||:|:.|||||||||||:|||.|.:|...|.|.::|||.|::|||
Zfish   341 VFDYHSDDVYWCTADIGWITGHSYITYGPLANGATSVLFEGLPTYPDVSRMWEIVDKYHVSKFYT 405

  Fly   378 APTAIRALMKFGEGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGH 442
            ||||||.|||:|..||.|:..:.||:||:||||||||||.|||..:|:::|.:||||||||||||
Zfish   406 APTAIRLLMKYGSDPVHKYKRTSLKILGTVGEPINPEAWQWYYNVVGEKRCPVVDTFWQTETGGH 470

  Fly   443 VITPLPGATPMKPGSASFPFFGVKPTLLDECGIEIKGEGEGYLVFSQPWPGMMRTLYNNHERFED 507
            |:||||.|||||||||:||||||.|.:|:|.|.|::|..||||||.|||||:|||:|.||.|||.
Zfish   471 VMTPLPAATPMKPGSATFPFFGVVPAILNESGEELEGPSEGYLVFKQPWPGVMRTVYGNHLRFET 535

  Fly   508 TYFSKFPGYYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRP 572
            |||.||||||.||||.|||.|||.|||||:||||||||||:|||||||.|.||..|||:|||.||
Zfish   536 TYFKKFPGYYVTGDGCRRDKDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGRP 600

  Fly   573 HPVKGECLYCFITPNENEVFDQKLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLR 637
            ||||||.||||:|.|:...::|||.::|||.|||:||..|.||.|||||||||||||||||||||
Zfish   601 HPVKGESLYCFVTLNDGINYNQKLEAELKKQVREKIGAIATPDYIQNAPGLPKTRSGKIMRRVLR 665

  Fly   638 KIAVNDRNVGDTSTLADEQIVEQLFANR 665
            |||.|:|::||.|||||..::|.||.||
Zfish   666 KIACNERDLGDVSTLADSSVIEHLFENR 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_730611.1	ACS	24..654	CDD:341270	409/655 (62%)
acss2	NP_001315282.1	ACS	28..682	CDD:341270	409/655 (62%)