Protein Alignment AcCoAS and Acsm3

DIOPT Version :10

• Sequence 1: NP_730611.1
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_006230168.1
• Gene: Acsm3 / 24763
• RGDID: 62086
• Length: 581
• Species: Rattus norvegicus
• Alignment Length: 648
• Identity: 182/648 - (28%)
• Similarity: 279/648 - (43%)
• Gaps: 101/648 - (15%)

  Fly     6 SIYDPNPAISQNAYISSFEEYQKFYQESLDNPAEFWSRVAKQFHWETPADQDKFLKYNFNISKGP 70
            :|.||...:        :::|:....::..|    :..:...|..|.|       :| ||.:|..
  Rat    14 AIPDPRRIL--------YKDYRTAIPQNFSN----YESMKHDFKIEIP-------EY-FNFAKDV 58

  Fly    71 ISIKWMEGASTNLCYNLLDRNVRNGLGDQIAYYW-EGNHPDDYSRGLTYRKLLEEV----CRFAN 130
            :. :|.....|.       :.:.|.     |::| :||       |...|...||:    .:|||
  Rat    59 LD-QWTNTEKTG-------KRLSNP-----AFWWVDGN-------GKEVRWSFEELGSLSRKFAN 103

  Fly   131 VLKDH-GIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITA 194
            :|.:. .:::||||.:.:|.|.|..:|.:||.|.|.|........:...:..|:...|:|.:||.
  Rat   104 ILTEACSLQRGDRVMVILPKIPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKSKCIITD 168

  Fly   195 DGAWRGEKPLYLKALCDTALEKVEEMGHSVEKCIVVSHLKRVTPCQPDHVEEEIPWTDDRDYWWH 259
            |         .|....|....|.|.: ||  |.||..|.:...    .:::|.:.:..|.    |
  Rat   169 D---------TLAPAVDIVAAKCENL-HS--KLIVSQHSREGW----GNLKEMMKYASDS----H 213

  Fly   260 EEMEDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDIYWC 324
            ..::.|.          .:.:.:.:|||:||.||.:.||.:.:.|..:...:...|....|:.|.
  Rat   214 TCVDTKH----------NELMAIYFTSGTTGPPKMIGHTHSSFGLGLSVNGRFWLDLIASDVMWN 268

  Fly   325 TGDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALMKFG 389
            |.|.||.......|:.|...|| .|.....|.|.... ....:.|:.:|.|.:||||.|.|::
  Rat   269 TSDTGWAKSAWSSVFSPWTQGA-CVFAHYLPRFDSTS-ILQTLSKFPITVFCSAPTAYRMLIQ-- 329

  Fly   390 EGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGATPMK 454
            ......:..:.||...|.|||||||....:.|..|.:   |.:.:.||||  .:|........:|
  Rat   330 NDITRSYKFNSLKHCVSAGEPINPEVMEQWKKKTGLD---IYEGYGQTET--VLICGNFKGMKIK 389

  Fly   455 PGSASFPFFGVKPTLLDECGIEIKGEGEGYLVF----SQPWPGMMRTLYNNHERFEDTYFSKFPG 515
            |||...|.......:|||.|..:....||.:..    .:|: |:.....:|..:...|....|
  Rat   390 PGSMGKPSPAFNVEILDENGTILPPGQEGDIAVQVLPDRPF-GLFTHYVDNPSKTASTLRGNF-- 451

  Fly   516 YYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECL 580
             |.|||....|.|||.|...|.||::..||:.:...||||.|.|||.:|||||||.|.|::||.:
  Rat   452 -YITGDRGYMDEDGYFWFVARSDDVILSSGYRIGPFEVESALIEHPSIAESAVVSSPDPIRGEVV 515

  Fly   581 YCFITPN-ENEVFDQKLISDLKKMVRERI----GPFAMPDVIQNAPGLPKTRSGKIMRRVLRK 638
            ..||..| :.::.||:   .|||.::|.:    .|:..|..|:....||||.|||:.|..||:
  Rat   516 KAFIVLNPDYKLHDQE---QLKKEIQEHVKKTTAPYKYPRKIEFIEELPKTVSGKVKRNELRR 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_730611.1	ACS	24..654	CDD:341270	179/630 (28%)
Acsm3	XP_006230168.1	MACS_euk	48..578	CDD:341251	175/602 (29%)