Protein Alignment AcCoAS and AcCoAS

DIOPT Version :10

• Sequence 1: NP_730611.1
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_316594.2
• Gene: AcCoAS / 1277153
• VectorBaseID: AGAMI1_003733
• Length: 669
• Species: Anopheles gambiae
• Alignment Length: 668
• Identity: 546/668 - (81%)
• Similarity: 609/668 - (91%)
• Gaps: 3/668 - (0%)

  Fly     1 MPAE-KSIYDPNPAISQNAYISSFEEYQKFYQESLDNPAEFWSRVAKQFHWETPADQDKFLKYNF 64
            ||:| :.|::|:|.::..|||:|.::|::|||:||:||.:||:.||||||||||.|...|..|||
Mosquito     1 MPSEPEKIFNPHPDVASKAYINSMQQYREFYQQSLENPGQFWANVAKQFHWETPYDPKNFFSYNF 65

  Fly    65 NISKGPISIKWMEGASTNLCYNLLDRNVRNGLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFA 129
            :||||||.:|||||||||:|||||||||:|||||.:|||||||||||||| ||||||||||||||
Mosquito    66 DISKGPIYVKWMEGASTNICYNLLDRNVKNGLGDTVAYYWEGNHPDDYSR-LTYRKLLEEVCRFA 129

  Fly   130 NVLKDHGIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITA 194
            ||||.||::|||||||||||.:|||:||||||||||||||||||||.|||||||.||:||:||||
Mosquito   130 NVLKSHGVQKGDRVSIYMPMTMELPVAMLACARIGAVHSIVFAGFSSDSLAERMHDCQAKVLITA 194

  Fly   195 DGAWRGEKPLYLKALCDTALEKVEEMGHSVEKCIVVSHLKRVTPCQPD-HVEEEIPWTDDRDYWW 258
            ||||||||.|:||.:||||::|.||:||.|:.||||||:.||||.:.| ....:.||.|.||:||
Mosquito   195 DGAWRGEKILHLKDICDTAMDKAEELGHHVQTCIVVSHINRVTPGKEDWDGSFDTPWRDGRDFWW 259

  Fly   259 HEEMEDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDIYW 323
            |:||||.|||||||||.|||||||||||||||||||||||||||||||||||||||||||.||||
Mosquito   260 HQEMEDAEPACYPEWMSAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPNDIYW 324

  Fly   324 CTGDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALMKF 388
            ||.|:|||||||||:|||||||||||:||||||||..||||.:||||||:||||||||||:||||
Mosquito   325 CTADIGWITGHTYVLYGPLANGATSVMFEGTPFFPDTDRYWEIIDKYKVSQFYTAPTAIRSLMKF 389

  Fly   389 GEGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGATPM 453
            |:.|||||:||.|:||||||||||||||||||:.||||:||||||||||||||||||||||||||
Mosquito   390 GDEPVLKHDLSSLRVLGSVGEPINPEAWLWYYRVIGKERCSIVDTFWQTETGGHVITPLPGATPM 454

  Fly   454 KPGSASFPFFGVKPTLLDECGIEIKGEGEGYLVFSQPWPGMMRTLYNNHERFEDTYFSKFPGYYC 518
            |||||||||||||||||||.|.||.||||||||||||||||||||:|||.|:|.||||||.||||
Mosquito   455 KPGSASFPFFGVKPTLLDESGTEITGEGEGYLVFSQPWPGMMRTLFNNHPRYESTYFSKFNGYYC 519

  Fly   519 TGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCF 583
            ||||||||||||.|:|||||||||||||||||:||||||||||||:|:|||||||||||||||||
Mosquito   520 TGDGARRDADGYFWVTGRVDDMLNVSGHLMSTSEVESVLTEHPRVSEAAVVSRPHPVKGECLYCF 584

  Fly   584 ITPNENEVFDQKLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLRKIAVNDRNVGD 648
            ||||:||.||:.|||:||.:|||||||||.|||||:|||||||||||||||||||:|||||:|||
Mosquito   585 ITPNQNEAFDKTLISELKVLVRERIGPFAQPDVIQHAPGLPKTRSGKIMRRVLRKVAVNDRDVGD 649

  Fly   649 TSTLADEQIVEQLFANRP 666
            |||||||.|:||||||||
Mosquito   650 TSTLADEAIIEQLFANRP 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_730611.1	ACS	24..654	CDD:341270	524/630 (83%)
AcCoAS	XP_316594.2	ACS	25..655	CDD:341270	525/630 (83%)