Protein Alignment AcCoAS and acsm3

DIOPT Version :10

• Sequence 1: NP_730611.1
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001104706.1
• Gene: acsm3 / 100002035
• ZFINID: ZDB-GENE-080220-22
• Length: 591
• Species: Danio rerio
• Alignment Length: 659
• Identity: 182/659 - (27%)
• Similarity: 275/659 - (41%)
• Gaps: 114/659 - (17%)

  Fly    17 NAYISSFEEYQKFYQESLDNPAEFWSRVAKQFHWETPADQDKFLKY-------------NFNISK 68
            |.|:.|...:::..:.|..|......:..:...::|.|.:: |..|             .||.:|
Zfish     2 NLYVFSNHVFKRCLKNSQRNEVYARGQWLQTCRFKTSAPKN-FSDYESMRSTYKIQVPQRFNFAK 65

  Fly    69 GPISIKWMEGASTNLCYNLLDRNVRNGLGDQI-AYYWEGNHPDDYSRGLTYRKLLEEV----CRF 128
            ..:. ||             :...::|....: |.:|..:|      |...|...||:    .:.
Zfish    66 DVLE-KW-------------ETKEKSGQRSSLPALWWVNDH------GTEVRWSFEELGFHSRKL 110

  Fly   129 ANVLKD-HGIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLI 192
            ||||:. ..:.:||||.:.:|.:.|..:..:||.|.|.|.....:..:...:..|:....||.:|
Zfish   111 ANVLRQVCSLERGDRVFLILPRVPEWWLVNVACIRTGTVLIPGTSQLTARDMRHRLITSGAKCVI 175

  Fly   193 TADGAWRGEKPLYLKALCDT-ALEKVEEMGHSVEKCIVVSH------------LKRVTPCQPDHV 244
            |.:         .|..|.|| ||:     ..|:...:::||            :.||:   .|||
Zfish   176 TDE---------TLAPLLDTVALD-----CPSISTKLLLSHKPMDGWGNLTELMGRVS---DDHV 223

  Fly   245 EEEIPWTDDRDYWWHEEMEDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATT 309
                                    |..  ..:|:|:.:.:|||:||.||...|:...|.|.....
Zfish   224 ------------------------CVD--TSSEEPMTIFFTSGTTGSPKMTQHSHCSYGLGLTVN 262

  Fly   310 FKIVFDYKPGDIYWCTGDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQ 374
            .:...|....|::|.|.|.||.......|:.|...|| .|.....|.|..| .....:..|.:|.
Zfish   263 GRYWLDLTEQDVFWNTSDTGWAKSAWSSVFAPWIQGA-CVFVHHMPRFDTN-TVLKTLSHYPITT 325

  Fly   375 FYTAPTAIRALMKFGEGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTET 439
            |.|||||.|.|:   :..:.|:....|:.....|||||||....:.:..|.:   |.:.:.||||
Zfish   326 FCTAPTAYRMLV---QDDLSKYKFQALEHCLCAGEPINPEVMCKWKELTGLD---IYEGYGQTET 384

  Fly   440 GGHVITPLPGATPMKPGSASFPFFGVKPTLLDECGIEI-KG-EGEGYLVFSQPWPGMMRTLYNNH 502
              .:|........:||||......|....::||.|..: || ||:..:......|..:.|.|...
Zfish   385 --VLIAGTFKGMKIKPGSFGKASPGYDVQVVDENGSVVPKGQEGDLGIRVKPERPFSLFTEYTGE 447

  Fly   503 E-RFEDTYFSKFPGYYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAES 566
            . |..:.:...|   |.|||....|.:||||..||.||::..:|:.:...|||:.|.|||.||||
Zfish   448 PVRTAECFRGDF---YLTGDRGMMDDEGYLWFIGRSDDVILSAGYRIGPFEVENALIEHPAVAES 509

  Fly   567 AVVSRPHPVKGECLYCFI--TPNENEVFDQKLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSG 629
            ||||.|.||:||.:..|:  |.:......::||.:|:..|:....|:..|..|:....||||.||
Zfish   510 AVVSSPDPVRGEVVKAFVVLTADFKSRAHKELIKELQTHVKSITAPYKYPRKIEFVDQLPKTVSG 574

  Fly   630 KIMRRVLRK 638
            ||.|..|||
Zfish   575 KIRRVELRK 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_730611.1	ACS	24..654	CDD:341270	179/652 (27%)
acsm3	NP_001104706.1	MACS_euk	57..586	CDD:341251	173/603 (29%)