Protein Alignment CG10508 and Wwc3

DIOPT Version :10

• Sequence 1: NP_001246859.1
• Gene: CG10508 / 40342
• FlyBaseID: FBgn0037060
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: NP_001414540.1
• Gene: Wwc3 / 317439
• RGDID: 1560666
• Length: 1214
• Species: Rattus norvegicus
• Alignment Length: 795
• Identity: 144/795 - (18%)
• Similarity: 253/795 - (31%)
• Gaps: 254/795 - (31%)

  Fly     9 KMPPGWDCKYDQATGNCYYINYLTKAMQLEDPRGRSYRQLQNERCSTESIALQQLVSQPQTSHNS 73
            ::|.||:..||:..| .||::::.|..|:||||.:..|  :.||...|.:    :|:|...:...
  Rat   107 ELPLGWETVYDKQIG-IYYMDHINKLTQIEDPREQWRR--EQERMLKEYL----IVAQEALNAKK 164

  Fly    74 SPYHVHPSNNLTAIRAFQERQQPTLHNI-------------------------------STSPLL 107
            ..|.:.......|...:|:     ||.:                               |....|
  Rat   165 EIYQIKQQRFELAQEEYQQ-----LHKLCEDDGRSYTSSFSGYSTNTKYDPHQIKAEIASRRDRL 224

  Fly   108 SASSRGHLEMSSPLPFQRARVGPNLSRRSTIQE------TSFTTQA--ETDAVVTKIQNMFPT-- 162
            |...|...:|...|.::...|       .|:||      .:.||..  |..|::::::.:...
  Rat   225 SRLKRELAQMKQELQYKEKGV-------ETLQEIDRKMSNTHTTYKLDEAQAIMSELRTIKKAIC 282

  Fly   163 AGENHIRLLLKRY------YNSEAVVVSALQVEKHPVTMPGPFVTPPSQRHLFHSGSAFYMTPPA 221
            .||...|.|::..      :.:...:|..|....|            |...|.:||::.......
  Rat   283 TGEKERRDLMQSLAKLTDSFKNSCSIVDTLPDFSH------------STGSLGNSGASQQFCDAG 335

  Fly   222 RRPDTV-----------------------ASRRTSRTASPLPGGRFGSLVSVQSGPGGPSGHQAV 263
            .:.|||                       |.:|.|.....|      :.::.:|.||
  Rat   336 SQTDTVGEFLFDDKTRLVDRVRLNWQYEEARKRVSNIQQQL------AQLANESWPG-------- 386

  Fly   264 LPPSSAVPPALHGSPLWRSSPRPHSSPKMKLRYMKNIFPKADEELLLDILANAD-NNVQFASEKL 327
                                                             :|.|| :.:|...||.
  Rat   387 -------------------------------------------------MAEADRDRLQLIKEKE 402

  Fly   328 ISLGYTKRDMQQPHRPNNRPPDLNQDQEAGGDQSGVHIPLRPKEYTEEEKTKMQTLLKEKYPQIA 392
            ..|...:..:|| .|.......|.:::....|:      ::....|..:....:.||:||
  Rat   403 ALLQELQLIIQQ-RRSAEDVVRLEEERRRLEDE------IQRARATSAQGATERILLQEK----- 455

  Fly   393 ERIILMALESVNYAEDRATQILQIVQDEDEQREQKQAPMNPKHLDLKK-TTGTEQIDGANEKDSL 456
            ...:||.||       .||::...:|.:                 ||. :..|..:...:.:.||
  Rat   456 RNCLLMQLE-------EATRLTSYLQSQ-----------------LKSLSASTLTVSSGSSRGSL 496

  Fly   457 PAVVEPTTSSKPKPPHKRHILPSINVTTPSTFTTQIILAQATPTPTPTAEEMKLETHLSSISSAS 521
                   .||:......|..|.||      :||....|.|.........:.::.:  |....|..
  Rat   497 -------ASSRGSLASSRGSLSSI------SFTDIYGLPQYEKADAECGQLLRFD--LIPFESLG 546

  Fly   522 SSHSYASPPQSPRIFQQSYERLTTKSILAKSGHNHFGHQSDTNNYSIDGYLHGSSNASSYSSYSA 586
            ....: :.|||...|.:..:.|.|...||.                    |...|:.||.|..|:
  Rat   547 RDVPF-TDPQSHSGFHKQRKSLDTPQSLAS--------------------LSSRSSLSSLSPPSS 590

  Fly   587 SMTSSSLVSSAQSNSSSIARRPAFESRARTKTDSLKHRQHSLGNSHNSESAEFQSIIERMASLGP 651
            .:.:..|.:|..|..:.:.  ..:|:......|.|:.:..:||:.....||..|.....:...||
  Rat   591 PLDTPFLTASRDSPLAQMT--DTYEAAGLGTLDRLRSQASTLGDEDLQGSAILQPHGIPVDGEGP 653

  Fly   652 NSQLSKGADENLLLADYVTWNGPNTKLLQKQITQG----PNASLLTDR-TYKPRGGKSELCKGPQ 711
            .   .:|.......:..||....:.|.|:::..:.    .:.||.:|. .::|...::|..:.|
  Rat   654 R---ERGPQPVAPTSATVTLREDSAKRLERRARRVSACLSDYSLASDSGVFEPLTKRNEDAEEP- 714

  Fly   712 SGLAKGSIYAQGSNK 726
               |.|.:|  |:|:
  Rat   715 ---AFGDMY--GNNE 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10508	NP_001246859.1	CUE	291..327	CDD:270465	5/36 (14%)
Wwc3	NP_001414540.1	None