Protein Alignment park and Rnf14

DIOPT Version :10

• Sequence 1: NP_730600.1
• Gene: park / 40336
• FlyBaseID: FBgn0041100
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_064396.2
• Gene: Rnf14 / 56736
• MGIID: 1929668
• Length: 485
• Species: Mus musculus
• Alignment Length: 534
• Identity: 103/534 - (19%)
• Similarity: 165/534 - (30%)
• Gaps: 208/534 - (38%)

  Fly    22 GGKT-----LTHTLSIYVKTNTGKT---------------LTVNLE--PQWDIKNVKELVAPQLG 64
            ||:|     |.....|:|..|:.::               |.:|.|  |.:...:..........
Mouse    33 GGETRIYLDLPQNFKIFVSGNSNESLQNSGFEYTICFLPPLVLNFELPPDYPSSSPPSFTLSGKW 97

  Fly    65 LQPDDLK-----------------IIFAGKELSDATTIE--------QCDLGQQSVLHAIRLRPP 104
            |.|..|.                 ::||..:.....|:.        :..:|.|.         .
Mouse    98 LSPTQLSALCKHLDNLWEEHRGRVVLFAWMQFLKEETLTYLNIVSPFELKMGSQK---------K 153

  Fly   105 VQRQKIQSATLEEEEPSLSDEASKPLNETLLDLQLESEERLNITDEERVRAKAHFFVHCSQC--D 167
            |||:....|: ...|..:...|:..::      |.|:.:...:.|.|.:.:.....:..:|.  .
Mouse   154 VQRRATAQAS-SSTELGVGGAAAADVD------QEETVDERAVQDVESLSSLIQEILDFNQARQT 211

  Fly   168 KLCNGKLRVRCALCKGGAFTVHRDPECWDDVLKSRRIPGHCESLEVACVDNAAGDPPFAEFFFKC 232
            |..|.||.: |::|                         .||.|...|:           :|.:|
Mouse   212 KCFNSKLFL-CSIC-------------------------FCEKLGSDCM-----------YFLEC 239

  Fly   233 AEHVSGGEKDFAAPLNLIKNNIKNVPCLAC------TDVSDTVLVFPCASQHVTCIDCFRHYCRS 291
                                  |:|.|.||      ..:.|         ..|.|::|
Mouse   240 ----------------------KHVYCKACLKDYFEIQIKD---------GQVKCLNC------- 266

  Fly   292 RLGERQFMPHPDFGYTLPCPAGCEHSFIEEIHHFKLLTREEYDRYQRFATEEYVLQAGGVLCPQP 356
                    |.|.      ||:......::|:....|..|  |||....:|.:  |.|..|.||:|
Mouse   267 --------PEPQ------CPSVATPGQVKELVEADLFAR--YDRLLLQSTLD--LMADVVYCPRP 313

  Fly   357 GCGMGLLVEPDCRKVTCQNGCGYVFCRNCLQGYHIGECLPEGTGASATNSCEYTVDP-----NRA 416
            .|.:.::.||......| :.|.:.||..|...||            ..:.|:.|.:.     |..
Mouse   314 CCQLPVMQEPGGTMAIC-SSCNFAFCTLCRLTYH------------GLSPCKVTAEKLIDLRNEY 365

  Fly   417 AEARWDEA----------------------SNVTIKVSTKPCPKCRTPTERDGGCMHMVCTRAGC 459
            .:|  |||                      |...::.::|.||.|.||.::..||..|.||  ||
Mouse   366 LQA--DEATKRFLEQRYGKRVIQKALEEMESKDWLEKNSKSCPCCGTPIQKLDGCNKMTCT--GC 426

  Fly   460 GFEWCWVCQTEWTR 473
            ...:||:|....:|
Mouse   427 MQYFCWICMGSLSR 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
park	NP_730600.1	Ubl_parkin	32..105	CDD:340496	15/114 (13%)
		RING0_parkin	159..250	CDD:412057	13/92 (14%)
		zf-RING_14	249..337	CDD:465601	19/93 (20%)
		BRcat_RBR_parkin	322..398	CDD:439001	22/75 (29%)
		Rcat_RBR_parkin	428..481	CDD:439018	17/46 (37%)
Rnf14	NP_064396.2	RWD_RNF14	9..135	CDD:467656	16/101 (16%)
		D-box	37..45		1/7 (14%)
		RING-HC_RBR_RNF14	214..272	CDD:438290	22/146 (15%)
		TRIAD supradomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01221	217..458		71/334 (21%)
		BRcat_RBR_RNF14	301..357	CDD:439002	18/70 (26%)
		Rcat_RBR_RNF14	390..457	CDD:439015	18/53 (34%)