DRSC/TRiP Functional Genomics Resources

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Protein Alignment park and C17H11.6

DIOPT Version :10

Sequence 1:NP_730600.1 Gene:park / 40336 FlyBaseID:FBgn0041100 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_001123112.1 Gene:C17H11.6 / 181076 WormBaseID:WBGene00015926 Length:893 Species:Caenorhabditis elegans


Alignment Length:490 Identity:115/490 - (23%)
Similarity:167/490 - (34%) Gaps:175/490 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 EQCDLGQQSVLHAIRLRPPVQ-RQKIQ---SATLE---EEEPSLSDEASKPLNETLLDLQLESEE 143
            |:..:..|.:||.  ..|||| |:||.   |||..   ...||.|.|:|...|..          
 Worm    13 EEPSIESQPILHT--ATPPVQHRRKISEEVSATRPCQIRATPSKSTESSSVANVG---------- 65

  Fly   144 RLNITDEERVRAKAHFFVHCSQCDKLCNGKLRVRCALCKGG--AFTVHRDPECW---DD------ 197
              :|....|...|             |..:|.:...|...|  :|:..|....|   ||      
 Worm    66 --SIVANHRPSRK-------------CGSRLSLTSLLSFTGHSSFSRDRSRSGWSYSDDNAGHVA 115

  Fly   198 ---------------VLKSRRIPGHCESLEVACVDNAAGDPPFAEFFFKCAEHV----------S 237
                           .:.|:|..|   |...:.:|:.||:        .|||.:          .
 Worm   116 MTSVSSSDVRSNVSGSISSKRYRG---SDTGSGMDSEAGE--------TCAEMLLSSRNQDDEEQ 169

  Fly   238 GGEKDFAAPL-----------NLIKNNIKNVP-CLACTDVSDTVLVFP----CASQHVTCIDCFR 286
            ..||..:..|           ...|..:|..| |.|....|    .||    |  ||.:|..|.|
 Worm   170 SDEKQLSQSLPDTPKTPSEVGKKGKGKMKECPLCAAKMPGS----AFPKLKGC--QHRSCRACLR 228

  Fly   287 HYCRSRLGERQFMPHPDFGYTLPCPAGCEHSFIEEIHHFKLLTRE---EYDRYQRFATEEYVL-Q 347
            .|....:.|.:        ..:|||   |.|.....:..|:|..:   ..::|:.|:...|:: :
 Worm   229 QYVELSITENR--------VEVPCP---ECSSYLHPNDIKMLIGDIPTLIEKYEAFSLRRYLMTE 282

  Fly   348 AGGVLCPQPGCGMGLLVE--PDCRKVTCQN-GCGYVFCRNCLQGYHIGECLPEGTGASATNSCEY 409
            |....||.|.||...:..  ..|.::.||. .||.:||.:|.:.:|..:                
 Worm   283 ADARWCPAPDCGFVFIATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQ---------------- 331

  Fly   410 TVDPNRAAEAR--------------WDEASNVTIKV-STKPCPKCRTPTER--DGGCMHMVCTRA 457
            |.|..|..|.|              :.::::.|:|. ..|.||:|:|...:  ||.|.|||||. 
 Worm   332 TCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHMVCTM- 395

  Fly   458 GCGFEWCWVCQTE-------------------WTR 473
             |..|:||:|..|                   |||
 Worm   396 -CNAEFCWLCLKEISDLHYLSPTGCTFWGKKPWTR 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
parkNP_730600.1 Ubl_parkin 32..105 CDD:340496 5/18 (28%)
RING0_parkin 159..250 CDD:412057 22/137 (16%)
zf-RING_14 249..337 CDD:465601 23/95 (24%)
BRcat_RBR_parkin 322..398 CDD:439001 20/82 (24%)
Rcat_RBR_parkin 428..481 CDD:439018 24/68 (35%)
C17H11.6NP_001123112.1 RING_Ubox 199..260 CDD:473075 20/77 (26%)
BRcat_RBR_RNF19 266..339 CDD:438999 21/88 (24%)
Rcat_RBR_RNF19 367..435 CDD:439016 22/65 (34%)
MFS <435..>522 CDD:475125
Blue background indicates that the domain is not in the aligned region.

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