Protein Alignment CG10587 and TMPRSS11D

DIOPT Version :10

• Sequence 1: NP_001137989.2
• Gene: CG10587 / 40318
• FlyBaseID: FBgn0037039
• Length: 289
• Species: Drosophila melanogaster
• Sequence 2: NP_004253.1
• Gene: TMPRSS11D / 9407
• HGNCID: 24059
• Length: 418
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 83/296 - (28%)
• Similarity: 132/296 - (44%)
• Gaps: 53/296 - (17%)

  Fly    19 VLAQDLNQT--IDVNKLAKIVQ----------------RPGFQT----RVVGGDVTTNAQLGG-- 59
            ||.|.||.:  :::|...:|..                .|...|    |::||   |.|:.|.
Human   138 VLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLITLSEQRILGG---TEAEEGSWP 199

  Fly    60 YLIALRYEMNFVCGGTLLHDLIVLTAAHCFLGRVKISDWLAVGGASKLNDRGIQRQVKEVIKSAE 124
            :.::||......|||:|::::.:|||||||.......||:|..|.|....: ::.:|:.::....
Human   200 WQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGISTTFPK-LRMRVRNILIHNN 263

  Fly   125 FREDDMNMDVAILRLKKPMK-GKSLGQLIL--CKKQLMPGTELRVSGWGLTENS-EFGPQKLLRT 185
            ::......|:|::||:..:. .|.:..:.|  ..:.:.||:...|:|||..|.: ...|:  ||.
Human   264 YKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPE--LRQ 326

  Fly   186 VTVPVVDKKKCRASYLPTDWESHKHFDLFLKVHLTDSMFCAGV-LGKKDACTFDSGGPLVYKNQ- 248
            ..|.::....|.|        .|.:....|     ..|.|||| .|..|||..|||||||.::.
Human   327 GQVRIISNDVCNA--------PHSYNGAIL-----SGMLCAGVPQGGVDACQGDSGGPLVQEDSR 378

  Fly   249 ----VCGIVSFGIGCASKRYYGVYTDIMYVKPFIEQ 280
                :.||||:|..|......||||.:.....:|.|
Human   379 RLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQ 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10587	NP_001137989.2	Tryp_SPc	45..278	CDD:214473	72/244 (30%)
TMPRSS11D	NP_004253.1	SEA	48..146	CDD:460188	5/7 (71%)
		Tryp_SPc	187..415	CDD:238113	73/247 (30%)