DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10587 and Tmprss11b

DIOPT Version :10

Sequence 1:NP_001137989.2 Gene:CG10587 / 40318 FlyBaseID:FBgn0037039 Length:289 Species:Drosophila melanogaster
Sequence 2:NP_795998.2 Gene:Tmprss11b / 319875 MGIID:2442893 Length:416 Species:Mus musculus


Alignment Length:281 Identity:77/281 - (27%)
Similarity:131/281 - (46%) Gaps:28/281 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 LLTAP--LASIEVLAQDLNQTIDVNKLAKIVQRPGFQTRVVGGDVTTNAQLGGYLIALRYEMNFV 71
            |.|.|  |...|:...|..:.|: |:..:..:......|:.||. |.:.....:..:||......
Mouse   147 LTTDPGSLKLTEISKVDAEKIIN-NRCGRRPRMSATYDRITGGS-TAHKGEWPWQASLRVNGKHY 209

  Fly    72 CGGTLLHDLIVLTAAHCFLGRVKISDWLAVGGASKLNDRGIQRQVKEVIKSAEFREDDMNMDVAI 136
            ||.:|:.:..:|||||||.|.....: |.|...:::....:|..|:|:|...::.:.:.:.|||:
Mouse   210 CGASLIGERFLLTAAHCFQGTNNPKN-LTVSFGTRVTPAYMQHSVQEIIIHEDYVKGEHHDDVAV 273

  Fly   137 LRL-KKPMKGKSLGQLILCKKQLM--PGTELRVSGWGLTENSEFGPQKLLRTVTVPVVDKKKCRA 198
            ::| :|......:.::.|.:...:  ||..:.|:|||....:...| .||:..::.::|...|.:
Mouse   274 IKLTEKVSFNNDVHRVCLPESTQIFPPGEGVVVTGWGSFSYNGKSP-LLLQKASIKIIDTNTCNS 337

  Fly   199 SYLPTDWESHKHFDLFLKVHLTDSMFCAGVL-GKKDACTFDSGGPLVYKNQ-----VCGIVSFGI 257
            .      |::..       .:.|:|.|||.| |..|||..|||||||:.|.     :.||||:|.
Mouse   338 E------EAYGG-------RIVDTMLCAGYLEGSIDACQGDSGGPLVHPNSRDIWYLVGIVSWGH 389

  Fly   258 GCASKRYYGVYTDIMYVKPFI 278
            .|......|||..:...:.:|
Mouse   390 ECGRVNKPGVYMRVTSYRNWI 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10587NP_001137989.2 Tryp_SPc 45..278 CDD:214473 68/241 (28%)
Tmprss11bNP_795998.2 SEA 46..143 CDD:460188
Tryp_SPc 185..413 CDD:238113 68/242 (28%)
Blue background indicates that the domain is not in the aligned region.

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