Protein Alignment CG32432 and lrp1bb

DIOPT Version :10

• Sequence 1: NP_649266.1
• Gene: CG32432 / 40310
• FlyBaseID: FBgn0052432
• Length: 1307
• Species: Drosophila melanogaster
• Sequence 2: XP_073769005.1
• Gene: lrp1bb / 559293
• ZFINID: ZDB-GENE-070912-401
• Length: 4666
• Species: Danio rerio
• Alignment Length: 1122
• Identity: 206/1122 - (18%)
• Similarity: 337/1122 - (30%)
• Gaps: 366/1122 - (32%)

  Fly   214 CSLAEFSCSNGR-CVPLSKYCNNLNDCGDGSDEPRFC----TRCNRTYYGDIGQTYALELHRPKQ 273
            |.|....|...| |:..:|.||...||.||.||...|    :.|:             |||
Zfish   106 CPLNHIQCVGSRKCIHFNKLCNGAKDCEDGFDEGVHCRELLSACH-------------ELH---- 153

  Fly   274 DRVPFVCVLT------FTAAG----------------GQHGDVVQVTLDSFTIGRFTSYVHEGCP 316
              ..:.|::|      |.|.|                ..:|...|..::  |.|.|..    .|.
Zfish   154 --CRYGCIMTRNGTFCFCADGFEVGEDGRSCRDHDECAMYGTCSQTCMN--TYGSFRC----SCT 210

  Fly   317 DGYMQIAESARTPIGGMWCGSSWGPVLFYSETRSLIFTIRLNRLAR----DQSG-YNFDFRIRYK 376
            ||: .:..:.|:.|.....|.|...:|.......:|..:..:||..    |.:| :..||..:.:
Zfish   211 DGF-SLQPNRRSCIAKHEPGESPAALLIGGSDNIIITALNGSRLQTLKQLDSNGTHGLDFNHKEE 274

  Fly   377 ----VLSRDSSVTRYGGIKLAELAQWHNRSSFLNQQQQQQQQQQQQQQQQQGAPGILEDFTNSSV 437
                |.|.:||    |.::.|.:.:   .|.|..:|:.:..|......|      :..|:...:.
Zfish   275 SVCWVTSSESS----GQLRCARMKK---ASGFTKEQEVKTVQNLHDVDQ------LTFDWLTGNF 326

  Fly   438 ARSDRYGQDFSLFSAYANNKTFMASL--EKSLAKDEQNYTEPKYYLGDLIPGTYCSRIFSDCDKK 500
                       .|...|:::.|:.:.  :..:...:.:...||....|.:.|..   .|:|.. .
Zfish   327 -----------YFVDQASDRIFVCNQLGDTCVTVVDLDLLNPKAIALDPLMGML---FFTDYG-N 376

  Fly   501 PCRLQSPNFPGIYPRNLTCYYAVRQHDVPHGKHALILVKQPKGNLVWISTQETAAANKMAPPPSA 565
            ..:|:..|..|.....|..|...|...|     ||.|||
Zfish   377 VAKLERCNMDGTNRTRLVDYKVERPTAV-----ALDLVK-------------------------- 410

  Fly   566 SDKDKKFEPRLKTW--NYCDYIQENVKPKWKSTDYVTVYDGYTTRDPIILKFCGGGQAVPAAVSS 628
                     :|..|  .|.|||:        ..||
Zfish   411 ---------KLVYWADAYLDYIE--------MVDY------------------------------ 428

  Fly   629 GPELLVEFSTSPFGTFTGTSSQVLPLYGFQLEVEVQFVDIQSPTYSKNKKPCEFWIRGAGRGILE 693
                            .|.:...: :.|:|:.
Zfish   429 ----------------NGKNRHTI-MQGYQVA--------------------------------- 443

  Fly   694 SPKHSLAPNSTCLYHLQGLGVFKTFDHLSLSRRTSSQSGMHQPLSRFKVWISVLKFNLDPEFGQI 758
                          ||.||.||:  |:|..:|..:|...:          :.:|:.|   .|...
Zfish   444 --------------HLHGLAVFE--DYLYATRSEASSGTV----------VDILRIN---RFNVT 479

  Fly   759 DETSVGAIGVLQTQEDCSGMLRIWDGTLRDAPVCKDLNCATETSSYNTLGHYTH---NSTSVIAR 820
            |...:.:||..:|       :|::....:  |..|...|  |..||...|..:|   .|.|..:|
Zfish   480 DPEMLTSIGNAKT-------IRVYHKLCQ--PKVKGHAC--EVDSYGKPGGCSHICLLSGSYKSR 533

  Fly   821 FCR-------GTIPRTCDRSNINETY-----ARPCTIS--ESYVSTSDAITLELRNTESTVLRPL 871
            .||       |...::|.:.. |:.:     .||..|.  :..|.:||...:.:.:..:.  |.|
Zfish   534 SCRCRTGFRLGNDGQSCKKPK-NDLFLFYGKGRPGIIRGLDMNVKSSDEHMVPIEDLVNP--RAL 595

  Fly   872 DFKLK---YEFIDLHQ--------DGLPWGGGEHDCNRK-FLSSMMDRKDPAIFRSVRNIFLFGR 924
            |:..:   ..|.|...        ||         .||: .|...:|..:......:.|...:..
Zfish   596 DYHAETGNIYFADTTSFLIGRQKVDG---------SNRETILKDDLDNVEGISVDWIGNNLYWTN 651

  Fly   925 GGTRNLKCIYKFEAQRGERVRIKMRKVTTTNRPCYSR--VDEDINRSFCYGDTNVRIEIFERPYH 987
            .|.|....:.:.|...      :.||........:.|  |.:.:|....:.|..      |...:
Zfish   652 DGYRKTISVARLERAS------ETRKTLLEGDMSHPRAIVVDPLNSWMYWTDWE------EDEVN 704

  Fly   988 DSILLHRGCMCNSSNQSHLPVEYTSTSRDVEVHFIAQNM-----TTLDDPDTVNF--EGMFEFVK 1045
            |||........:.||:.               .|:..||     .|||...:..:  :..::.::
Zfish   705 DSIGRIEKAWMDGSNRK---------------IFVTSNMLWPNGLTLDHGTSTMYWCDAYYDHIE 754

  Fly  1046 APTSCKDGRRKFGPSGTIDMTFGDVECRSRPWLIEPSNGNKFLYVRLKA---IFLSKHNPTQTLN 1107
            .......||........::..||..:.::..:..|..|.:.|....|.|   :..|:..|...|.
Zfish   755 KIYLNGTGRMVVYSGRELNHPFGIAQYQNSIFWTEYMNASIFQLDLLSAEVSLLRSERPPLFGLR 819

  Fly  1108 ATYVQT---------DTWRCETKSRAVLTTSEGLTIVACPLSPDSNAYEFVEIFSSGWNE----R 1159
            ....|:         :...|.|...||    .|..:.||..:...:.:......|:|..|    |
Zfish   820 VYDAQSQLGDNPCRVNYGGCGTLCLAV----PGGRVCACADNQHLDKHNLTCSDSAGQEEPQRCR 880

  Fly  1160 PNFALVNRSRAISVEFLRPGNGEYSFNWMELIPRPTLSMAEDC---QFKCAELGACVNASVWCDG 1221
            .:.......|.|.|.::..|:.:......|   .|.:.....|   ||||.. ..|:.....|||
Zfish   881 SDEFQCRNGRCIRVNWICDGDDDCLDGSDE---EPHICSNHSCPIDQFKCPS-NRCIPKRWLCDG 941

  Fly  1222 VVHCPSGDDETFLQCSA 1238
            ...|...:||:...|||
Zfish   942 ADDCGDNEDESNKTCSA 958

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32432	NP_649266.1	LDLa	214..245	CDD:197566	12/31 (39%)
		CUB	503..646	CDD:238001	20/144 (14%)
		LDLa	1203..1231	CDD:197566	9/27 (33%)
lrp1bb	XP_073769005.1	None