Protein Alignment CG32432 and yl

DIOPT Version :10

• Sequence 1: NP_649266.1
• Gene: CG32432 / 40310
• FlyBaseID: FBgn0052432
• Length: 1307
• Species: Drosophila melanogaster
• Sequence 2: XP_310672.6
• Gene: yl / 1271818
• VectorBaseID: AGAMI1_010770
• Length: 1906
• Species: Anopheles gambiae
• Alignment Length: 1386
• Identity: 265/1386 - (19%)
• Similarity: 383/1386 - (27%)
• Gaps: 539/1386 - (38%)

  Fly   132 QHQQRRHPLPATLTLLLCLGISLGMAATAAAAGGGGGGGGGAAPVSGSGAAGFPSSSSSISSSLG 196
            |..::|:|..||...|:.|..::.:.|...:||
Mosquito    38 QEGEKRNPFAATNMRLVVLVATVVLLAANVSAG-------------------------------- 70

  Fly   197 PGKPVNLQLAPGSSSTGCSLAEFSCSNGRCVPLSKYCNNLNDCGDGSDE---------PRFCTRC 252
               .|..:....::|..|...||.|.||.|:|.:.:||::.||.|||||         ..|..||
Mosquito    71 ---KVESEKKSTAASKSCGAHEFQCENGACIPAAGHCNDIQDCADGSDESGCDYFLCRAPFWYRC 132

  Fly   253 NR----------------TYYGDIGQ---TYALELHRPKQDRVPFVCVLTFTAAGGQHGDVVQVT 298
            ..                ...||..:   .|.:....|...:..|.|............|.||..
Mosquito   133 RHESTCISGSSRCDGQRDCLGGDDEENCDNYEVPHRAPLCSKAEFTCTDRACIPADLVCDGVQHC 197

  Fly   299 LDSF--TIG-------------------RFTSYVHEG---CPDG--------------------- 318
            ||..  |||                   :...:|.:|   |.||
Mosquito   198 LDGSDETIGCIDIAGKCKGFLCRNKHCLQSHHWVCDGLDDCGDGSDEEHCLSECTLEHGKYECAN 262

  Fly   319 ------YMQIAESA-------------RTPIGG---MWCGSSWGPVLFYSETRSLIFTIRLNRLA 361
                  ..|:...|             :.|..|   :.|......||...:...|
Mosquito   263 NHTCVDVTQVCNGADDCGDGSDEGPGCKVPADGCKALHCAPQTCKVLPDGKPVCL---------- 317

  Fly   362 RDQSGYNFDFR------------IRYKVLSRDSSVTRYGGIKLAELAQWH----NRSSFLNQQQQ 410
               .|..|.|.            .||.:.|: ..:...|..:...:.|:|    .|:..|:...:
Mosquito   318 ---CGVGFRFEPSAGRCVDVNECARYGLCSQ-GCINTPGSFRCTCIDQFHLMRDGRTCELSSGTE 378

  Fly   411 QQQQQQQQQQ---------QQQGAPGILEDFTNSSVARSDRYGQDFSLFSAYANNKTFMASLEKS 466
            .......|:.         .|......|......:...|..|..|.|       :||  .|:|:|
Mosquito   379 ALMLYTTQKAVGAMYLTSLHQYYVAKELSQVIGVAYDGSHVYWTDIS-------HKT--ESIERS 434

  Fly   467 LAKDEQNYTE--------PKYYLGDLIPGTYCSRIFSD--------C--DKKPCR------LQSP 507
            | :|..:..:        |:....|.:.|..   .|||        |  |...||      |..|
Mosquito   435 L-EDGSDRVQLLTAGLISPEDIALDWLTGNI---YFSDSGQMHIAVCSSDGYHCRAIVQDELHKP 495

  Fly   508 NFPGIYPRNLTCYYA-------------------VRQHDVPHGKHALILVKQPKGNLVWISTQET 553
            ....:.|:|.|.:|:                   |...|..|..:.|.| ..|...|.||
Mosquito   496 RGIALLPQNGTLFYSDWGNNAMIGRARMDGTEQQVVVSDGIHWPNGLTL-DWPNQRLYWI----- 554

  Fly   554 AAANKMAPPPSASDKDKKFEPRLKTWNYCDYIQENVKPKWKSTDYVTVYDGYTTRDPIILKFCGG 618
                           |.|.: |:::.::            ..||.|.|.|.       :||.
Mosquito   555 ---------------DAKLK-RIESMHF------------DGTDRVVVLDD-------VLKH--- 581

  Fly   619 GQAVPAAVSSGPELLV--EFSTSPFGT---FTGTSSQVLPLYGFQLEVEVQFVDIQ--------- 669
                |.:::...:.|.  ::.|....:   |||...|.|.......:|.|....||
Mosquito   582 ----PFSIAVFNDRLYWSDWDTKSIQSCDKFTGKMRQTLVHDRMIFDVHVYHSSIQPKVSHACAN 642

  Fly   670 -----------SPTYSKNKKPCEFWIRGAGRGI-LESPKHSLAPNSTCLYHLQGLGVF-KTFDHL 721
                       :.||:     |     ...:|: |...|||.|..:.....|.|:|.: .|..|.
Mosquito   643 HTCTHLCLLTSNATYA-----C-----ACPQGMELSRDKHSCASVAKRQDILLGIGHYLVTLKHH 697

  Fly   722 SLSRRTSSQSGMHQPLSRFKVWISVLKFN-LDPEFGQIDETS----VGAIGVLQTQEDC-SGMLR 780
            ...|..   :|..:||.  ...||.|.|| |..|....|.:.    ...:|.|:||... ||:.|
Mosquito   698 PFGRHA---TGRGEPLP--VATISRLAFNSLTGELFVADNSRRAIYTVELGSLRTQRLVRSGIGR 757

  Fly   781 I-------------WDGTLRDAPVCKDLNCATETSSYNTLGHYTHNSTSVIARFCRGTIPRT--- 829
            |             |....|.......|    :|...:.:.||..:...|    ....||.|
Mosquito   758 ITALAFDYLSNTLYWSDAERSTIEIYSL----QTRHRSIIQHYLGDDAPV----ALALIPETGKM 814

  Fly   830 ------------CDRSNINETYARPCTISESYVSTSDAITLELRNTESTVLRPLDFKLKYEFIDL 882
                        .||.::  |...|.|          .:..|...:..|:...:|..|:..|
Mosquito   815 FVALRSPSGHTHIDRQDM--TGRGPHT----------HVIEERLGSNGTISFAVDQDLRSVF--- 864

  Fly   883 HQDGLPWGGG----------EHDCNRKFLSSMMDRKDPAIFRSVRNIFLFGRGGTR-------NL 930
                  |...          |.|....|...:.:....||..|  .:|...||..|       |:
Mosquito   865 ------WSDSGTNRIEITSFEGDTRHLFREYLREPVSLAIIGS--ELFWTCRGSQRLYWSDKHNV 921

  Fly   931 KCIYKFEAQRGERVRIKMRKVTTTNRPCYSRVDEDINRSFCYGDTNVRIEIFERPYHDSILLHRG 995
            ....:...|....:.:........::|...|.|....||                       :.|
Mosquito   922 GATKRISVQLPPDLAVPDEMPIAASQPTTRRPDHPCTRS-----------------------NGG 963

  Fly   996 CMCNSSNQSHLPVE---YTSTSRDVEVHFIAQNM---TTLD----DPDTVNFEGMFEFVKAPTSC 1050
            |       ||:.|.   |||..      .....|   |||.    |.....|.           |
Mosquito   964 C-------SHICVAGGLYTSAC------VCPTGMVFNTTLARVCIDAAACAFR-----------C 1004

  Fly  1051 KDGR---RKFGPSGTID-MTFGDVE-CRSRPWLIEPSNGNKFLYVRLKAIFLSKHNPTQTLNATY 1110
            ..|.   |....:|.:| |...|.: |.|:    .|:..                      ..|.
Mosquito  1005 ASGECLARGLRCNGRVDCMDQSDEQGCESK----TPAGA----------------------GTTG 1043

  Fly  1111 VQTDTWRCETKSRAVLTTSEGLTIVACPLSPDSNAYEFVEIFSSGWNERPNFALVNRSRAISVEF 1175
            .:.:.:||...||.:..||.      |...||. |....|....|:|.|.|
Mosquito  1044 CRWNEFRCADGSRCIAATSR------CDSRPDC-ADRSDEANCEGYNRRTN-------------- 1087

  Fly  1176 LRPGNGEYSFNWMELIPRPTLSMAEDC---QFKCAELGACVNASVWCDGVVHCPSGDDETFLQCS 1237
                                      |   ||.||: |.||:|:..||.|..||.|.||.  :|:
Mosquito  1088 --------------------------CTRYQFSCAD-GFCVDATARCDQVPDCPDGSDEQ--ECA 1123

  Fly  1238 ALMKLPAEILATLCLIFVLSC 1258
            .:.. ...:.||.|...:..|
Mosquito  1124 GVGG-KGGVAATTCAAGMFRC 1143

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32432	NP_649266.1	LDLa	214..245	CDD:197566	15/30 (50%)
		CUB	503..646	CDD:238001	30/172 (17%)
		LDLa	1203..1231	CDD:197566	14/27 (52%)
yl	XP_310672.6	None