Protein Alignment HIPP1 and CDY1B

DIOPT Version :10

• Sequence 1: NP_649261.1
• Gene: HIPP1 / 40302
• FlyBaseID: FBgn0037027
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_001003895.1
• Gene: CDY1B / 253175
• HGNCID: 23920
• Length: 554
• Species: Homo sapiens
• Alignment Length: 544
• Identity: 107/544 - (19%)
• Similarity: 201/544 - (36%)
• Gaps: 69/544 - (12%)

  Fly   384 KRKIIWDPDVPETKKSFAQYASTKAACPAPTTPKTTVKSISPTTTTKKEVAPKKRSATPTARSTK 448
            |:...|:|:         |:......|......:.|.|....|.||...:. ...:...|:||||
Human    33 KQDDTWEPE---------QHLMNCEKCVHDFNRRQTEKQKKLTWTTTSRIF-SNNARRRTSRSTK 87

  Fly   449 AG-------TPVGGTERGPSPVKRRAQTPNTGLANGGTQKKKKVSEIDRLMGDEGAANMIHAVEH 506
            |.       |||         ..:..::.|..|.......::|.:.|   :.|.....:|::...
Human    88 ANYSKNSPKTPV---------TDKHHRSKNRKLFAASKNVRRKAASI---LSDTKNMEIINSTIE 140

  Fly   507 EQRELSGGEVSNKPLMRKRAMTITGRNQAARVAVEPTPPKKESAQSAAKRTPADSVFTKATANTS 571
            ..       ..:.|...|   |::|..:     :|...|.....|        |:|..|.|....
Human   141 TL-------APDSPFDHK---TVSGFQK-----LEKLDPIAADQQ--------DTVVFKVTEGKL 182

  Fly   572 ARKPRASDSWDYVYKQRASEESMIMRRRSNSSYSSNASVSRNSLDNRPGAANLSDDAGEGSDPSF 636
            .|.|.:....:....|..::...:|.:.|.|..:|.|:.|.    .|.|...|.|..........
Human   183 LRDPLSRPGAEQTGIQNKTQIHPLMSQMSGSVTASMATGSA----TRKGIVVLIDPLAANGTTDM 243

  Fly   637 KFVKPVSKSSQRGGEDTS---------SHTLANDMKANNGSELVCLHKVNKVAHLVIHTERGNFG 692
            ....|..|..||...|.|         ..|:.....|:...::| :.|.:....:|:.| |....
Human   244 HTSVPRVKGGQRNITDDSRDQPFIKKMHFTIRLTESASTYRDIV-VKKEDGFTQIVLST-RSTEK 306

  Fly   693 HTYSKQLLEQLNDTLSSVARKGEFNTVLLTVEGPQFCQGIDCQELIQGSLEKRKDSASQLAVALK 757
            :..:.::::::.:.|:|.| ..:...||.:..|..||.|:|....::.....|..::.::...:|
Human   307 NALNTEVIKEIVNALNSAA-ADDSKLVLFSAAGSVFCCGLDFGYFVKHLRNNRNTASLEMVDTIK 370

  Fly   758 CYLRTLATFPKPLVAGIVGSQINLGVMQLPFADYVVASDDCSFETNYAKLGQLPEGYALWHGHQR 822
            .::.|...|.||:|..:.|..|.||...||..|.|.|::...|:|.|...||.|:|.:.....:.
Human   371 NFVNTFIQFKKPIVVSVNGPAIGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKM 435

  Fly   823 VSSEVHSRLFLMGERLFATELLESNSFVDKICKARNVNEMALAKAKQISTSSAEMYRTLKKLNHS 887
            :.....:.:.:.|.:|.|.|.. :...|.::.......:..:.:.|::::.:..:....|.|...
Human   436 MGKASANEMLIAGRKLTAREAC-AKGLVSQVFLTGTFTQEVMIQIKELASYNPIVLEECKALVRC 499

  Fly   888 AVNVTKFPRLDEELKVIGEQWVTA 911
            .:.:......:.|.:|:.:.|.:|
Human   500 NIKLELEQANERECEVLRKIWSSA 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIPP1	NP_649261.1	PTZ00449	<148..580	CDD:185628	38/202 (19%)
		crotonase-like	673..870	CDD:119339	43/196 (22%)
CDY1B	NP_001003895.1	CD_CDY	5..56	CDD:349284	5/31 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..106		9/38 (24%)
		crotonase-like	286..482	CDD:119339	44/199 (22%)