DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HIPP1 and ech-3

DIOPT Version :9

Sequence 1:	NP_649261.1	Gene:	HIPP1 / 40302	FlyBaseID:	FBgn0037027	Length:	926	Species:	Drosophila melanogaster
Sequence 2:	NP_505066.1	Gene:	ech-3 / 179180	WormBaseID:	WBGene00001152	Length:	258	Species:	Caenorhabditis elegans

Alignment Length:	236	Identity:	49/236 - (20%)
Similarity:	83/236 - (35%)	Gaps:	48/236 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   670 LVCLHKVNKVAHLVIHTERGNFGHTYSKQLLEQLNDTLSSVARKGEFNTVLLTVEGPQFCQGIDC 734
            |:.:::.||         :....|..:.||:    |............|.:|..||..||.|.|.
Worm    17 LIGINRANK---------KNCVNHATALQLI----DAFEKFNEDSTMKTAVLYGEGGTFCAGYDL 68

  Fly   735 QELIQGSLEKRKDSASQLAVALKCYLRTLATFPKPLVAGIVGSQINLGVMQLPFADYVVASDDCS 799
            :.:   |..:.::.:.......:....::....|||:|.|.|..:..|:.....||..|:|....
Worm    69 ESV---SKAEHQEVSEDFCDKYRYMGPSIMKIKKPLIAAIEGFAVAGGLELSLMADLRVSSPSAK 130

  Fly   800 FETNYAKLG---------QLPE----GYALWHGHQRVSSEVHSRLFLMGERLFATELLESNSFVD 851
            |.....::|         :||.    |.||             .:.|.|..:.|.|.|:. ..|:
Worm   131 FGVFCRRVGVPLIDGGTVRLPRVIGLGRAL-------------DMILTGREVGAQEALQW-GLVN 181

  Fly   852 KICKARNVNEMALAKAKQISTSS-----AEMYRTLKKLNHS 887
            :|.......|.|:...|.|::..     |:...|...|.|:
Worm   182 RISDEGKAVEEAVKLGKLIASHPEICMLADRESTYYSLEHT 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HIPP1	NP_649261.1	crotonase-like	673..870	CDD:119339	43/209 (21%)
ech-3	NP_505066.1	crotonase-like	7..247	CDD:304874	49/236 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810