Protein Alignment CG11396 and Trappc12

DIOPT Version :10

• Sequence 1: NP_649255.1
• Gene: CG11396 / 40296
• FlyBaseID: FBgn0037022
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_001385710.1
• Gene: Trappc12 / 314013
• RGDID: 1566054
• Length: 797
• Species: Rattus norvegicus
• Alignment Length: 571
• Identity: 186/571 - (32%)
• Similarity: 278/571 - (48%)
• Gaps: 109/571 - (19%)

  Fly     6 SEYFANDPP----------SFFDELASKPKGNNLSTEGSSSSASST----------SSAPNMMSN 50
            ||..|..||          :||.:..|   .|:|:::...|..:||          |..|..:::
  Rat   239 SETSAKTPPPMVQPSPSLSTFFGDTMS---SNSLASDFFDSFTTSTFISVSNPNAGSPVPEKLAS 300

  Fly    51 TF--VGFFQP----PEY---------------VETPEAGE-----DSIKVGDD-----VRNLWEL 84
            ..  ||...|    |.|               ::.||:.:     .::..|.|     ..::.|:
  Rat   301 LTAPVGEKSPDSTSPSYSTRMDRSESGVSRAALDVPESPKPFSQIQAVFAGSDDPFATALSMSEM 365

  Fly    85 PRENE---PGK-----------------------LIMPGIHLQTDLADPISVAVTQHLGEAELSY 123
            .|.|:   |.:                       |.|||:.......|.:...:.:.|||...:.
  Rat   366 DRRNDAWLPSQATREVLMSVATQQYGTVFIDKENLTMPGLKFDNIQGDAVKDLMLRFLGEKAAAK 430

  Fly   124 RKILRVDDVTQDERGLRTLIHAGCYRTAVNLTGRLLTIYGQGYGRSGQPAKHSPHSLQLWFTRLA 188
            |::|....|.|...||:.||....:|.||:|.|||||.:|||||:||.|..|:..||||||.|||
  Rat   431 RQVLNASSVEQSFVGLKQLISCRNWRAAVDLCGRLLTAHGQGYGKSGLPTNHTTDSLQLWFVRLA 495

  Fly   189 LLAKLGEFELLNAEAEPFGQLTSPDVFYDFYPEMYNGKSGSIACFSFRLLLAELPIYLGKPHVAL 253
            ||.|||.|:....|.||||.|..||::|::||.:|.|:.||:..||.|:|.|||..|||.|..:|
  Rat   496 LLVKLGLFQNAEMEFEPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSMRILHAELQQYLGNPQESL 560

  Fly   254 DRLSELHVTTREI---------KEHYLSL----HNKAAEEFWQRRCERVLHSIINCGLMMKKFSM 305
            |||..:.....:|         ::..||.    ..:|:.:.|:.|..|||:|:.||.|:||.:.:
  Rat   561 DRLHRVKTVCSKILANLEQGLAEDGGLSSVTQESRQASVQLWRSRLGRVLYSMANCLLLMKDYVL 625

  Fly   306 -IDDIMEGTLLKRSNLSKEDRRSLYSAWGRIYLQIGDIFGAEQKI----AVSRRLREINSAPDLR 365
             ::..:  |::|   ...|....|.|..|||.||||||..||:..    .|:::|..:..  .:.
  Rat   626 AVNAYL--TVIK---YYPEQEPQLLSGIGRILLQIGDIKTAEKYFQDVEKVTQKLDGLQG--KIM 683

  Fly   366 DLVDKGLIAVAKNDFPEAYVIFQKALHLDTGNTMILNNMGVCLLYAGKLKDAINLYERAINLNPQ 430
            .|:::..:.:.:|:|.||:..|.:.|.:|..|.:..||..|||||.|||||::...|..:..:|:
  Rat   684 VLMNRAFLYLGQNNFAEAHKFFTEILRMDPTNAVANNNAAVCLLYLGKLKDSLRQLEAMVQQDPR 748

  Fly   431 KSLNESLLVNLSTLYELESNNSKAKKYNLLRLINRYKPD-LNISIEICLKL 480
            ..|:||:|.||:|:|||||:.|..||.:||..:...:.| .|..   ||||
  Rat   749 HYLHESVLFNLTTMYELESSRSMQKKQSLLEAVASKEGDSFNTQ---CLKL 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11396	NP_649255.1	TPR repeat	328..357	CDD:276809	15/32 (47%)
		TPR	329..>457	CDD:440225	51/131 (39%)
		TPR repeat	367..392	CDD:276809	6/24 (25%)
		TPR repeat	397..427	CDD:276809	14/29 (48%)
Trappc12	NP_001385710.1	PHA03247	<202..366	CDD:223021	25/129 (19%)
		BepA	604..749	CDD:443813	51/151 (34%)
		TPR repeat	608..635	CDD:276809	10/28 (36%)
		TPR repeat	641..675	CDD:276809	14/33 (42%)
		TPR repeat	680..710	CDD:276809	6/31 (19%)
		TPR repeat	716..740	CDD:276809	12/23 (52%)