Protein Alignment CG11396 and Trappc12

DIOPT Version :10

• Sequence 1: NP_649255.1
• Gene: CG11396 / 40296
• FlyBaseID: FBgn0037022
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_001363935.1
• Gene: Trappc12 / 217449
• MGIID: 2445089
• Length: 798
• Species: Mus musculus
• Alignment Length: 557
• Identity: 184/557 - (33%)
• Similarity: 274/557 - (49%)
• Gaps: 90/557 - (16%)

  Fly     2 SHKISEYFANDPPS------FFDEL------------ASKPKGNNLST----EGSSSSASSTSSA 44
            |..:|.:|.:...|      |||..            |..|....||:    .|..|..|::.|.
Mouse   253 SPSLSTFFGDTMSSNSLASDFFDSFTTSTFISVSNPNAGSPVPEKLSSLTAPVGEKSPDSTSPSY 317

  Fly    45 PNMMSNTFVGFFQPPEYVETPEAGE-----DSIKVGDD-----VRNLWELPRENE---PGK---- 92
            ...|..:..|..:.|  ::.||:.:     .::..|.|     ..::.|:.|.|:   |.:
Mouse   318 STRMDRSESGVSRAP--LDVPESPKPFSQIQAVFAGSDDPFATALSMSEMDRRNDAWLPSQATRE 380

  Fly    93 -------------------LIMPGIHLQTDLADPISVAVTQHLGEAELSYRKILRVDDVTQDERG 138
                               |.|||:.......|.:...:.:.|||...:.|::|....|.|...|
Mouse   381 VLMSVATQQYGTVFIDKENLTMPGLKFDNIQGDAVKDLMLRFLGEKAAAKRQVLNASSVEQSFVG 445

  Fly   139 LRTLIHAGCYRTAVNLTGRLLTIYGQGYGRSGQPAKHSPHSLQLWFTRLALLAKLGEFELLNAEA 203
            |:.||....:|.||:|.|||||.:|||||::|.|..|:..||||||.|||||.|||.|:....|.
Mouse   446 LKQLISCRNWRAAVDLCGRLLTAHGQGYGKNGLPTSHTTDSLQLWFVRLALLVKLGLFQNAEMEF 510

  Fly   204 EPFGQLTSPDVFYDFYPEMYNGKSGSIACFSFRLLLAELPIYLGKPHVALDRLSELHVTTREI-- 266
            ||||.|..||::|::||.:|.|:.||:..||.|:|.|||..|||.|..:||||..:.....:|
Mouse   511 EPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSMRILHAELQQYLGNPQESLDRLHRVKTVCSKILA 575

  Fly   267 -------KEHYLSL----HNKAAEEFWQRRCERVLHSIINCGLMMKKFSM-IDDIMEGTLLKRSN 319
                   ::..||.    ..:|:.:.|:.|..|||:|:.||.|:||.:.: :|..:  |::|
Mouse   576 NLEQGLAEDGGLSSVTQESRQASVQLWRSRLGRVLYSMANCLLLMKDYVLAVDAYL--TVIK--- 635

  Fly   320 LSKEDRRSLYSAWGRIYL-QIGDIFGAEQKI----AVSRRLREINSAPDLRDLVDKGLIAVAKND 379
            ...|....|.|..|||.| |||||..||:..    .|:::|..:..  .:..|:::..:.:.:|:
Mouse   636 YYPEQEPQLLSGIGRILLQQIGDIKTAEKYFQDVEKVTQKLDGLQG--KIMVLMNRAFLYLGQNN 698

  Fly   380 FPEAYVIFQKALHLDTGNTMILNNMGVCLLYAGKLKDAINLYERAINLNPQKSLNESLLVNLSTL 444
            |.||:..|.:.|.:|..|.:..||..|||||.|||||::...|..:..:|:..|:||:|.||:|:
Mouse   699 FAEAHKFFTEILRMDPTNAVANNNAAVCLLYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLTTM 763

  Fly   445 YELESNNSKAKKYNLLRLINRYKPD-LNISIEICLKL 480
            |||||:.|..||.:||..:...:.| .|..   ||||
Mouse   764 YELESSRSMQKKQSLLEAVASKEGDSFNTQ---CLKL 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11396	NP_649255.1	TPR repeat	328..357	CDD:276809	15/33 (45%)
		TPR	329..>457	CDD:440225	51/132 (39%)
		TPR repeat	367..392	CDD:276809	6/24 (25%)
		TPR repeat	397..427	CDD:276809	14/29 (48%)
Trappc12	NP_001363935.1	PHA03307	1..>380	CDD:223039	26/128 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..257		1/3 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	286..338		12/53 (23%)
		TPR 1	607..640		12/37 (32%)
		TPR	608..>765	CDD:440225	58/163 (36%)
		TPR repeat	608..635	CDD:276809	11/28 (39%)
		TPR repeat	641..676	CDD:276809	14/34 (41%)
		TPR repeat	681..711	CDD:276809	6/31 (19%)
		TPR 3	683..716		8/32 (25%)
		TPR 4	717..750		14/32 (44%)
		TPR repeat	717..741	CDD:276809	12/23 (52%)