Protein Alignment CG13251 and ccdc66

DIOPT Version :10

• Sequence 1: NP_649246.1
• Gene: CG13251 / 40286
• FlyBaseID: FBgn0037014
• Length: 1088
• Species: Drosophila melanogaster
• Sequence 2: XP_004914234.1
• Gene: ccdc66 / 733901
• XenbaseID: XB-GENE-6459434
• Length: 971
• Species: Xenopus tropicalis
• Alignment Length: 1138
• Identity: 222/1138 - (19%)
• Similarity: 367/1138 - (32%)
• Gaps: 400/1138 - (35%)

  Fly    60 SQTSTSNQTSSHSRRAPGPDMQLILR--QPEYSQDNQGYMNQLERYIDDLDGDADADFEDEDESM 122
            ||...|.||::....|.|..::...|  ||..:|.|         .:.:|:....|....::..:
 Frog    48 SQVLKSVQTNNVKPEAAGQRIKSGSRDGQPSKAQVN---------VLKELENKHQAPVLQQNVQL 103

  Fly   123 YRRTRRGSYAPGMSSRQMQNPARYAELVPTSLQTAKGRMQNSRQEAQQHLKHQHQQLL-LQQQQH 186
            :::.      ||.:..|.:.|            |..|..:..|.:.:...:...:.|: |.|:|.
 Frog   104 HKQD------PGKAKAQPKRP------------THSGAPRQQRSQPKVSAEQLRESLVCLTQEQF 150

  Fly   187 QQ------------QQQQR----------------------LRSPSL------------------ 199
            ||            .|.||                      |.||.|
 Frog   151 QQILMTINQGNKIITQDQRESDAPEAGTEENTTEPARNENVLASPDLDPKAAEQSTDVYNTRLQG 215

  Fly   200 ---PAIRQRVRHQDSRTGKPT----DID-----------PGNGPHRLNNPPGGAGNPPGGGGGA- 245
               ..:.:|.|.:.....|.|    ::|           ...|..|.:...|.:.:.|||....
 Frog   216 DLFSTLGERERDKSLEEAKKTKWRKELDEQIATKKRLRESAQGGWRYSRHQGMSSSEPGGCDSVQ 280

  Fly   246 PGPPGCQEEDTSGYLSDTPKNPHTPDIWFNDGASQIESISGMGSASVLDGGSVGAVGGGVAGCRR 310
            |..|..|::.   |.||. ..|...|:.|....|...|.|   |..||.|.|    |.|
 Frog   281 PSLPEAQKDP---YSSDR-GTPAQDDMLFGTSTSTETSDS---SPIVLSGPS----GRG------ 328

  Fly   311 LRRSIQAGTSGAPIPAPI--------PMPLPHHQPPPGNPLGKIYTIKGRRVPGQGYEPLAADGY 367
                  :..|...:||.|        ..|:.|       |...|    .|:...:..|.|.....
 Frog   329 ------SSFSSPELPAAIRSAFVLGEAAPMDH-------PFSAI----KRQQQKKWLEELNKQRE 376

  Fly   368 MA------------------------DGYCYMPAPPSSSNMSMSRDVSTSNTYQVHIGNPDQNDF 408
            .|                        |.:..:..|.:.:..:.:..:.|.|..      |.|.
 Frog   377 EAVLRKKLEKKKMLEMEETEKWAMHFDSFKKISDPQTQAPYTPAELLQTQNLL------PAQR-- 433

  Fly   409 FVHEQHERERARWANFNGGAGHQAAQQP---PGWLS----RGMHDLKDSEDDVQSMQSSSTYLRG 466
                               ..|.|:.:|   |. ||    .|...|:.|:|:     ..:.:||.
 Frog   434 -------------------TAHSASAEPSVTPD-LSPTQCAGSELLRSSQDN-----QKTGFLRT 473

  Fly   467 QNAPLDAHTLAERMDKRRKAAEYHNAIKKQLHERELIRKWEHERHRQEEQIEEERIRRQKQLEQE 531
            ..|.||...:.||..||.|..|:..||..|:.|:...::.|.|:.::|||.||:::..::  ||.
 Frog   474 MTALLDPAQIEEREQKRLKQLEHQKAIAAQVEEKRRRKQLEEEQKQREEQEEEQKLAMER--EQM 536

  Fly   532 RLEFERRTLQER--EEAQQKKQQVMLDAIQKAEVAAKMERQKRRMVRQPSKVSQETEEDESELIR 594
            ..:||..|.::|  ||..:.|.:.:.:::|:|:..|:..:|::||        :..|....::.:
 Frog   537 HRQFEEDTKRQRQKEEMLKLKTKELYESMQRAQEEAQRLKQQQRM--------RHLEHKGHDIFQ 593

  Fly   595 VQSVEEE--EDAE---EKSGA-------VEPPSQEEETSN-------TPRGAPPVMSEE---KVL 637
            :|..::.  |.|:   .::|:       :.|||.....:.       :||....|.::|   .|.
 Frog   594 LQRNDDTHGEAAQLDASRAGSRSTDTTPLYPPSVANSAATHVPDVLVSPRKDTAVQTDEVDRGVT 658

  Fly   638 IGTPINLRRTITKPIKQPRDSRKEDPKEPTQTKVQ----------TTFLGEDKENVALLMQPATL 692
            :|..:        |.|.....|...|:.|.:.|.|          ::...|:||
 Frog   659 VGAAL--------PAKDAVWGRSPSPEVPIEFKAQGRKPRSLRERSSSRKENKE----------- 704

  Fly   693 IPLPVTSDIFGLQNAIGNLQIATYFMQPP--MQKPPE--TPGS--YSKATMTHRTDTSIYTEDGY 751
              ||  .|.:. |.|....|......:|.  ..|||.  .|.|  |.|               |.
 Frog   705 --LP--HDYYE-QFARAERQAKEPAQKPDWNKNKPPRRFVPASERYPK---------------GL 749

  Fly   752 QAEKEEDPLTTARSGRTDLVTASGCFSPDSLEVDVAPVLIAETDKLALIPLKTPLQLGISNSSDD 816
            |.::||     :|..|                         :.:.:.|:....|     ||....
 Frog   750 QRQREE-----SRVRR-------------------------QHELMHLLEKNAP-----SNLQPK 779

  Fly   817 RGEHNHEVGHQADVETQTELPLNCDLCLFHDNFYKVLLKREVSTTTTTQT------SKSQTQPAK 875
            :|:           ..:..||.:       |...|:|.|:.|......:.      |.|...||.
 Frog   780 KGD-----------SPKKSLPGD-------DAKGKLLAKKAVPEEPVEKAEPYIKRSDSPPVPAV 826

  Fly   876 ESTAEKDHETTTTTTTTTT--------TTFKAKSKDKDKEKNLKRNLN----------KDKDANK 922
            ::...:.|:...:|.|...        .|:....:|...|.:.:.:..          :.|:...
 Frog   827 KNRMHQSHKRQNSTATNAVYNGGAIQGGTYTVSQRDVSPESSEQESERPPSSNFIPYVRTKEVYY 891

  Fly   923 MD-DRPKWGVNRPVVQYVKASDRDPFCLRKKKNHPSTAKPPRSL-SMDSRLD-----SVALPEDR 980
            :| |.|   ::||       |..||     :...|...:..|.: |.|...|     ||...:||
 Frog   892 LDPDAP---MSRP-------STHDP-----QYQRPGDEQTTRQIFSSDHARDPLLNPSVVKNKDR 941

  Fly   981 LINIAGGPPSAAGELEEEGFLLKARNVCTEILP 1013
            ...|..|    ..|| .:|.|.|.:.:.|.::|
 Frog   942 QQAILKG----LSEL-RKGLLQKQKELETGLMP 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13251	NP_649246.1	CCDC66	445..580	CDD:434558	40/136 (29%)
		PTZ00121	<472..693	CDD:173412	57/254 (22%)
ccdc66	XP_004914234.1	CCDC66	456..593	CDD:434558	41/151 (27%)