Protein Alignment CG13251 and CCDC66

DIOPT Version :9

• Sequence 1: NP_649246.1
• Gene: CG13251 / 40286
• FlyBaseID: FBgn0037014
• Length: 1088
• Species: Drosophila melanogaster
• Sequence 2: NP_001340076.1
• Gene: CCDC66 / 285331
• HGNCID: 27709
• Length: 954
• Species: Homo sapiens
• Alignment Length: 642
• Identity: 131/642 - (20%)
• Similarity: 234/642 - (36%)
• Gaps: 194/642 - (30%)

  Fly   445 HDLKDSEDDVQSMQSSSTYLRGQNAPLDAHTLAERMDKRRKAAEYHNAIKKQLHERELIRKWEHE 509
            |..|..:|.|.:....:.:||...|.||...:.||..:|:|..|:..||..|:.|:...::.|.|
Human   423 HIAKPIKDVVMANSKKTNFLRSMTALLDPAQIEERDRRRQKQLEHQKAITAQVEEKRRKKQLEEE 487

  Fly   510 RHRQEEQIEEERIRRQKQLEQERLEFERRTLQEREEAQQKKQQVMLDAIQKAEVAAKMERQKRRM 574
            :.::|||.||.|:.::::..|::.|.:....:::||....|...:...:|:|:..|:..:|::|
Human   488 QRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEEIMTLKTNELFQTMQRAQELAQRLKQEQR- 551

  Fly   575 VRQPSKVSQETEEDESELIR---------VQSVEEE----------EDAEEKSGAVEPPSQEEET 620
            :|:.::...:|    |.||:         |.:::.|          .|::|.||.:. ......|
Human   552 IRELAQKGHDT----SRLIKNLGGDFSLPVDTIQMEYNASNISNSRHDSDEISGKMN-TYMNSTT 611

  Fly   621 SNTPRGAPPVMSEEKVLIGTPIN--------LRRTITKPIKQP--------RDSRKEDPKEPTQT 669
            |....|    :..:.:.||...|        :.|.||. ...|        :.|.|::.:|.||.
Human   612 SKKDTG----VQTDDLNIGIFTNAESHCGSLMERDITN-CSSPEISAELIGQFSTKKNKQELTQD 671

  Fly   670 KVQTTFLGEDKENVALLMQPATLIPLPVTSDIFGLQNAIGNLQIATYFMQP-------PMQKPPE 727
            |..:.    :|||.....|                .|....::..|..|:.       .:.|||:
Human   672 KGASL----EKENNRCNDQ----------------CNQFTRIEKQTKHMKKYPKRPDWNINKPPK 716

  Fly   728 --TPGS--YSKATMTHRTDTSIYTEDGYQAEKEEDPLTTARSGRTDLVTASGCFSPDSLEVDVAP 788
              .|.|  |.|                 |.:|:.:.....|
Human   717 RYIPASEKYPK-----------------QLQKQREEKKVRR------------------------ 740

  Fly   789 VLIAETDKLALIPLKTPLQLGISNSSDDRGEHNHEVGHQADVETQTEL----------PLNCDLC 843
                :.:.|.|:....|..|     |.:|| .:.|:.|.:..||:::|          |||
Human   741 ----QMELLHLVEKNNPGHL-----SQNRG-ISPEIFHSSHQETESKLRWHLVKKEEEPLN---- 791

  Fly   844 LFHDNFYKVLLKREVSTTTTTQTSKSQTQ--------PAKESTAEKDHETTTTTTTTTTTTFKAK 900
             .|.      ..:|.|.::.....|::||        |.|.|:.|:::..:.:..|..::..
Human   792 -IHS------FSKERSPSSPVPVVKNRTQQTQNTLHLPLKNSSYERENLISGSNQTELSSGI--- 846

  Fly   901 SKDKDKEKNLKRNLNKDKDANKMD-DRPKWGVNRPVVQYVKASD-------RDPFCLRKKKNHPS 957
            |:.......::.|     :...:| |.|..|.:....||..:.|       .|..|:|....:|:
Human   847 SESSHFIPYVRTN-----EIYYLDPDAPLSGPSTQDPQYQNSQDCGQKRQLFDSDCVRDPLLNPN 906

  Fly   958 TAKPPRSLSMDSRLDSVALPEDRLINIAGGPPSAAGELEEEGFLLKARNVCTEILPI 1014
            ..|                ..||...|..|    ..|| .:|.|.|.:.:.:.:||:
Human   907 MVK----------------NRDRQQAILKG----LSEL-RQGLLQKQKELESSLLPL 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13251	NP_649246.1	CCDC66	445..580	CDD:291889	37/134 (28%)
CCDC66	NP_001340076.1	CCDC66	411..562	CDD:317619	37/139 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	458..499		14/40 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	696..719		5/22 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	794..814		4/25 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160161
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28UYI
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22736
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930