Protein Alignment Hpd and HPDL

DIOPT Version :9

• Sequence 1: NP_730536.1
• Gene: Hpd / 40263
• FlyBaseID: FBgn0036992
• Length: 380
• Species: Drosophila melanogaster
• Sequence 2: NP_116145.1
• Gene: HPDL / 84842
• HGNCID: 28242
• Length: 371
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 103/388 - (26%)
• Similarity: 173/388 - (44%)
• Gaps: 46/388 - (11%)

  Fly    13 AGKFLSFDHLTFYVGNAKQAASYYTTRLGFEPLGYQGLETGERRFAKHAVRQNKIVFVFVSAYTP 77
            |...|...|:.|:|...:..|.......||:||..:.:: |.|:.   |:|....||:.......
Human     2 AAPALRLCHIAFHVPAGQPLARNLQRLFGFQPLASREVD-GWRQL---ALRSGDAVFLVNEGAGS 62

  Fly    78 DDEEHGLHLMRHGDGVKDVAFEVEDLNAIFTLAVSRGAEVVRDIWEESDDQGFVRFATIKT-YGD 141
            .:..:||..........::.|:|.|..|......:.|..|........|.||...:|.:.: .|.
Human    63 GEPLYGLDPRHAVPSATNLCFDVADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPAGI 127

  Fly   142 TTHTFVERNGYAGDFLPGFQRSPKDVLLNGLPSTK-LNFIDHVV-----GNQPDLQMESVASWYE 200
            .:.|.:||.||.|.|||||:.      ::..|... ::.:||:.     |:.|.|     ..|:.
Human   128 LSLTLLERAGYRGPFLPGFRP------VSSAPGPGWVSRVDHLTLACTPGSSPTL-----LRWFH 181

  Fly   201 RILQF-HRFWSV-DDSQIHTEYSA------LR---------SIVMANYEETVKMPINEPANGKKK 248
            ..|.| |...|. :|.::..|.:|      ||         |||     .|:.:..:.|....::
Human   182 DCLGFCHLPLSPGEDPELGLEMTAGFGLGGLRLTALQAQPGSIV-----PTLVLAESLPGATTRQ 241

  Fly   249 SQIQEYVEYYGGGGVQHIALNTDDIIEAVSNLKARGTEFLTIPSSYYEILQEQLSHSRTKIKEDM 313
            .|:::::..:.|.|:||:.|.|.:|:||...:...|.:||..|.:||:  |............:.
Human   242 DQVEQFLARHKGPGLQHVGLYTPNIVEATEGVATAGGQFLAPPGAYYQ--QPGKERQIRAAGHEP 304

  Fly   314 EVLKKLNILIDFDENGYLLQIFTKNCQDRPTLFLEVIQRYNHNGFGAGNFKSLFTAIEIEQAK 376
            .:|.:..||:|.|:..:|||:|||:.....|.|||:|||....|||.||.::|:.:::.:.|:
Human   305 HLLARQGILLDGDKGKFLLQVFTKSLFTEDTFFLELIQRQGATGFGQGNIRALWQSVQEQSAR 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hpd	NP_730536.1	4HPPD	17..380	CDD:273528	102/384 (27%)
HPDL	NP_116145.1	4HPPD	10..368	CDD:273528	101/380 (27%)
		Glo_EDI_BRP_like	10..148	CDD:301325	38/141 (27%)
		HPPD_C_like	158..363	CDD:176673	61/216 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3185
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1087836at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820