Protein Alignment CG5618 and Hdc

DIOPT Version :10

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Alignment Length: 583
• Identity: 130/583 - (22%)
• Similarity: 221/583 - (37%)
• Gaps: 177/583 - (30%)

  Fly     7 GAETVDQIRDGLMDDWKILENVFHLLRKEDTFCVDPQKWDKQKIVPFLQPDKLKELINLKVRETE 71
            |.|.||.|.|       .|||:                 .::::.|.:.|..:::|:      .|
  Fly    10 GKEMVDYIAD-------YLENI-----------------RERRVFPDVSPGYMRQLL------PE 44

  Fly    72 NCSL---------AEIEELCQQ-VIHYSVKTSHGRFH--NQLFGQLDPFGLAGALVTEAMNGSTY 124
            :..:         :::|.:... :.|:.....|..|.  |.:     | .|.|.::.:|:|...:
  Fly    45 SAPIEGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALNSM-----P-SLLGDMLADAINCLGF 103

  Fly   125 TYEVAPVFSLIETEVIATICKLAG----------YKEGDGIFAPGGSTSNMYGMVLAR------- 172
            |:..:|..:.:|..|:..:.|:.|          ..:|.|:.....|.:.:..::..|
  Fly   104 TWASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRF 168

  Fly   173 ------YKIAPEVKTSGMFGMRPLVLFTSDESHYSFVKAANWLGLGSYNCVSVRTNE-------R 224
                  |:.| |:...       ||.:.||::|.|..||| .:||     |.:|..|       |
  Fly   169 HERHPGYQDA-EINAR-------LVAYCSDQAHSSVEKAA-LIGL-----VRMRYIEADDDLAMR 219

  Fly   225 GQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAAL 289
            |::|.:.:|..|.:    |..||:|..|.|||...:||::.....|...|.|||||||...|:|.
  Fly   220 GKLLREAIEDDIKQ----GLVPFWVCATLGTTGSCSFDNLEEIGIVCAEHHLWLHVDAAYAGSAF 280

  Fly   290 LSAKNRSLIAGLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFY--- 351
            :..:.|:.:.|:|||:|.::||.|.:......:....|:         ||..|..|..:..|
  Fly   281 ICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRD---------STAVHRTFNVEPLYLQH 336

  Fly   352 ---DVSYDTGNKSVQCGRKIDAFKFWLMLKARGYGKYGLM--VDHAIHIARLLEGKL-------- 403
               .|:.|..:..:...|:..|.|.|.:|  |.||..||.  :...:.:|:..|..:
  Fly   337 ENSGVAVDFMHWQIPLSRRFRALKVWFVL--RSYGIKGLQRHIREGVRLAQKFEALVLADHRFEL 399

  Fly   404 -----------RQRGDR-------FRLVIPEHEYSNVCFWFIPKAMR--------VSSEEET--- 439
                       |.|||.       .||   .|..:..|   ||.:::        ::|...|
  Fly   400 PAKRHLGLVVFRIRGDNEITEKLLKRL---NHRGNLHC---IPSSLKGQYVIRFTITSTHTTLDD 458

  Fly   440 -PEWWSRLYTVAPKIKEQM------------------AHSGTLMIGYSPLKAKNLGNFFRMVF 483
             .:.|..:..||..:.|:|                  |...:|::..|||..|.:...|..:|
  Fly   459 IVKDWMEIRQVASTVLEEMNITISNRVYLKETKEKNEAFGSSLLLSNSPLSPKVVNGSFAAIF 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	GadA	56..507	CDD:439846	120/534 (22%)
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	96/418 (23%)