Protein Alignment CG5618 and GAD2

DIOPT Version :10

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_000809.1
• Gene: GAD2 / 2572
• HGNCID: 4093
• Length: 585
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 36/198 - (18%)
• Similarity: 59/198 - (29%)
• Gaps: 83/198 - (41%)

  Fly    50 FSGLERVSSGSA--------TSFWHTAVSKSSQ---------STSINSS---------------S 82
            :|.:...|||||        ...:..|:.::.|         .||:||:               .
Human     4 YSTVPPPSSGSAGGGGGGVVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQ 68

  Fly    83 PEAKRCKLASESSPGDSCSNIDFVQVKAPTALEVSVASAESDLCLKLGKRTYSEEY--------- 138
            |:||:....::|          |.....|...:.|             :...:|||
Human    69 PDAKKVPPQNDS----------FGAQLPPMHQQQS-------------RSVMTEEYKVPDGMVGF 110

  Fly   139 -WGRNNNEISAVSMKLLTPSVVAGKSKLCGQSMPVPRCQIDGCELDLSSAK-------------- 188
             .||...:||.:..:......:|..|    ..:|...|.:.|....:.|||
Human   111 IIGRGGEQISRIQQESGCKIQIAPDS----GGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAP 171

  Fly   189 GYH 191
            |:|
Human   172 GFH 174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	GadA	56..507	CDD:439846	35/192 (18%)
GAD2	NP_000809.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		6/19 (32%)
		Pyridoxal_deC	138..509	CDD:395219	8/37 (22%)