DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5618 and Csad

DIOPT Version :9

Sequence 1:	NP_649211.1	Gene:	CG5618 / 40241	FlyBaseID:	FBgn0036975	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001346055.1	Gene:	Csad / 246277	MGIID:	2180098	Length:	493	Species:	Mus musculus

Alignment Length:	461	Identity:	228/461 - (49%)
Similarity:	320/461 - (69%)	Gaps:	8/461 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 QKIVPFLQPDKLKELINLKVRETENCSLAEIEELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAG 112
            :|:..:.:|::||:|::|:: :::..|..:|.|.|:.||||||||.|.||.||||..|||..|||
Mouse    41 EKVCEWKEPEELKQLLDLEL-QSQGESREQILERCRTVIHYSVKTGHPRFFNQLFSGLDPHALAG 104

  Fly   113 ALVTEAMNGSTYTYEVAPVFSLIETEVIATICKLAGYKEGDGIFAPGGSTSNMYGMVLARYKIAP 177
            .::||::|.|.||||:||||.|:|.||:..:..|.|:..|||:|.||||.||||.|.|||::..|
Mouse   105 RIITESLNTSQYTYEIAPVFVLMEEEVLKKLRALVGWNSGDGVFCPGGSISNMYAMNLARFQRYP 169

  Fly   178 EVKTSGMFGMRPLVLFTSDESHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEAKIAEAKAR 242
            :.|..|:..:.||.||||.|.|||..|.|.:||||:.:...|:.:|||:|:.:|||.:|..|:|.
Mouse   170 DCKQRGLRALPPLALFTSKECHYSITKGAAFLGLGTDSVRVVKADERGRMIPEDLERQIILAEAE 234

  Fly   243 GGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKNRSLIAGLERANSF 307
            |..||.|:.|:|||||||||.::..|||.:|||||.||||..||:.|||..:|.|:.|::||:|.
Mouse   235 GSVPFLVSATSGTTVLGAFDPLDAIADVCQRHGLWFHVDAAWGGSVLLSRTHRHLLDGIQRADSV 299

  Fly   308 SWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFYDVSYDTGNKSVQCGRKIDAFK 372
            :|||||.:.|.||||..|.|::..||:||:.::|.|||||||||||:.|||:|.|||||::|..|
Mouse   300 AWNPHKLLAAGLQCSALLLRDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLK 364

  Fly   373 FWLMLKARGYGKYGLMVDHAIHIARLLEGKLRQRGDRFRLVIPEHEYSNVCFWFIPKAMRVSSEE 437
            .|||.||:|.......:|.|..:.|.|..::::| :.|.||: |.|:.||||||:|.::|  .::
Mouse   365 LWLMWKAQGGQGLERRIDQAFALTRYLVEEIKKR-EGFELVM-EPEFVNVCFWFVPPSLR--GKK 425

  Fly   438 ETPEWWSRLYTVAPKIKEQMAHSGTLMIGYSPLKAKNLGNFFRMVFTCFPILKSKELDFILDEIE 502
            |:|::..||..|||.:||:|...||:||||.|...:  .|||||| ...|||...::||:|.|:|
Mouse   426 ESPDYSQRLSQVAPVLKERMVKKGTMMIGYQPHGTR--ANFFRMV-VANPILAQADIDFLLGELE 487

  Fly   503 RLGEKI 508
            .||:.:
Mouse   488 LLGQDL 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	206/406 (51%)
Csad	NP_001346055.1	DOPA_deC_like	89..481	CDD:99743	201/398 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62386
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	1	1.000	-	-		FOG0000667
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100596
Panther	1	1.100	-	-	LDO	PTHR45677
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.830