DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5618 and Ddc

DIOPT Version :9

Sequence 1:	NP_649211.1	Gene:	CG5618 / 40241	FlyBaseID:	FBgn0036975	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001257781.1	Gene:	Ddc / 24311	RGDID:	2494	Length:	480	Species:	Rattus norvegicus

Alignment Length:	454	Identity:	114/454 - (25%)
Similarity:	194/454 - (42%)	Gaps:	88/454 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GAETVDQIRDGLMDDWKILENVFHLLRKEDTFCVDPQKWDKQKIVPFLQPDKLKELINL---KVR 68
            |.|.||.|.|       .|:.:                 :.:.:.|.::|..|:.||..   :..
  Rat    10 GKEMVDYIAD-------YLDGI-----------------EGRPVYPDVEPGYLRALIPTTAPQEP 50

  Fly    69 ETENCSLAEIEELCQQ-VIHYSVKTSHGRFHNQLFGQLDPFGLA-GALVTEAMNGST----YTYE 127
            ||....:.:||::... |.|:         |:..|....|...: .|::.:.:.|:.    :::.
  Rat    51 ETYEDIIRDIEKIIMPGVTHW---------HSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWA 106

  Fly   128 VAPVFSLIETEVIATICK--------LAGYK-EGDGIFAPGGSTSNMYGMVLARYKI-------A 176
            .:|..:.:||.::..:.|        |||.. ||.|:.....|.:.:..::.||.|:       :
  Rat   107 ASPACTELETVMMDWLGKMLELPEAFLAGRAGEGGGVIQGSASEATLVALLAARTKMIRQLQAAS 171

  Fly   177 PEVKTSGMFGMRPLVLFTSDESHYSFVKAANWLGL-GSYNCVSVRTNERGQMLLDDLEAKIAEAK 240
            ||:..:.:  |..||.:|||::|.|..:|    || |.....::.::....|....|...:...|
  Rat   172 PELTQAAL--MEKLVAYTSDQAHSSVERA----GLIGGVKIKAIPSDGNYSMRAAALREALERDK 230

  Fly   241 ARGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKNRSLIAGLERAN 305
            |.|..||||..|.|||...:||::.....:..:.|:|||:||...|:|.:..:.|.|:.|:|.|:
  Rat   231 AAGLIPFFVVVTLGTTSCCSFDNLLEVGPICNQEGVWLHIDAAYAGSAFICPEFRYLLNGVEFAD 295

  Fly   306 SFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFY--DVSYDTG------NKSV 362
            ||::||||.:.....||....:      :|.:.|||   |..|..|  ....|:|      :..:
  Rat   296 SFNFNPHKWLLVNFDCSAMWVK------KRTDLTEA---FNMDPVYLRHSHQDSGLITDYRHWQI 351

  Fly   363 QCGRKIDAFKFWLMLKARGYGKYGLM--VDHAIHIARLLEGKLRQRGDRFRLVIPEHEYSNVCF 424
            ..||:..:.|.|.:.  |.||..||.  :...:.::...|..:|| ..||. :..|.....|||
  Rat   352 PLGRRFRSLKMWFVF--RMYGVKGLQAYIRKHVKLSHEFESLVRQ-DPRFE-ICTEVILGLVCF 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	96/360 (27%)
Ddc	NP_001257781.1	Pyridoxal_deC	35..414	CDD:278699	106/405 (26%)
Ddc	NP_001257781.1	2 X approximate tandem repeats	58..178		25/128 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810