DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5618 and Sgpl1

DIOPT Version :9

Sequence 1:	NP_649211.1	Gene:	CG5618 / 40241	FlyBaseID:	FBgn0036975	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001303602.1	Gene:	Sgpl1 / 20397	MGIID:	1261415	Length:	568	Species:	Mus musculus

Alignment Length:	429	Identity:	93/429 - (21%)
Similarity:	155/429 - (36%)	Gaps:	108/429 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 W-KILENVFHLLRK--------EDTFCVDPQKWDKQKIVPFLQPDKLKELINLKVRETENCSLAE 77
            | :..:.:|.|:||        |..  |...|.|..|.:|||:.||    ..:|....:....||
Mouse    67 WSRFKKKLFKLIRKMPFIGRKIEQQ--VSKAKKDLVKNMPFLKVDK----DYVKTLPAQGMGTAE 125

  Fly    78 IEELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAGA----------LVTEAMNGSTYTY----EV 128
            :.|..::             ::.:.|.......:||          |:.:|....|::.    ::
Mouse   126 VLERLKE-------------YSSMDGSWQEGKASGAVYNGEPKLTELLVQAYGEFTWSNPLHPDI 177

  Fly   129 APVFSLIETEVIATICKL-AGYKEGDGIFAPGGSTSNMYGMVLARYK-IAPEVKTSGMFGMRPLV 191
            .|....:|.|::...|.| .|..:..|....||:.|.:  |....|: :|.|.      |::...
Mouse   178 FPGLRKLEAEIVRMTCSLFNGGPDSCGCVTSGGTESIL--MACKAYRDLALEK------GIKTPE 234

  Fly   192 LFTSDESHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEAKIAEAKARGGEPFFVNCTAGTT 256
            :...:.:|.:|.|||::.|:   ..|.|...:..::.:..::..|:...|      .:.|:....
Mouse   235 IVAPESAHAAFDKAAHYFGM---KIVRVALKKNMEVDVQAMKRAISRNTA------MLVCSTPQF 290

  Fly   257 VLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKNRSLIAGLERA---------------NS 306
            ..|..|.:...|.:..|:.:.|||||||||         .||..:|:|               .|
Mouse   291 PHGVMDPVPEVAKLAVRYKIPLHVDACLGG---------FLIVFMEKAGYPLEKPFDFRVKGVTS 346

  Fly   307 FSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQ-------QDKFYDVSYDTGNKSVQC 364
            .|.:.||...||...|:.:           .|.|.:..:|       |...|......|::.
Mouse   347 ISADTHKYGYAPKGSSVVM-----------YSNEKYRTYQFFVGADWQGGVYASPSIAGSRP--- 397

  Fly   365 GRKIDAFKFWLMLKARGYGKYGLMVDHAIHIARLLEGKL 403
            |..|.|  .|..|...|...|.......|..||.|:.:|
Mouse   398 GGIIAA--CWAALMHFGENGYVEATKQIIKTARFLKSEL 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	74/345 (21%)
Sgpl1	NP_001303602.1	DOPA_deC_like	146..507	CDD:99743	73/331 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810