Protein Alignment CG5618 and hdl-2

DIOPT Version :10

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_501539.3
• Gene: hdl-2 / 182464
• WormBaseID: WBGene00006409
• Length: 611
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 108/555 - (19%)
• Similarity: 187/555 - (33%)
• Gaps: 150/555 - (27%)

  Fly    30 HLLRKEDTFCVD--PQKWDKQK----------------IVPFL---------QP-----DKLKEL 62
            |:||.|:....:  .|:.|:||                :|.|:         ||     |.....
 Worm    88 HVLRSENQAPTNEIQQRSDRQKLQEPIGKNEFIKCMSLVVQFINDYFDESHKQPVIPENDVNSSR 152

  Fly    63 INLKVRETENCSLAEI-EELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAGALVTEAMNGSTYTY 126
            |::||.|... .|.|| ::|.:.||.....|.|.|:|.:..|:    .||..:.:.......:..
 Worm   153 IHVKVPEKAE-ELTEILKDLKEIVIPNICHTHHPRYHAKFAGK----SLADLVASTISAALGHDV 212

  Fly   127 EVAPVFSLIETEVIATICK-LAGYKEGDGIFAPGGSTSNMYGMV----------LARYKIAPEVK 180
            ..:|:...||    ..||| |:.......|.:..|...:..|.|          :.|:.|....|
 Worm   213 NSSPIIESIE----RIICKWLSTSMAIPQIKSSLGELRDPIGTVFYTPCDVFISVIRHAIEKFEK 273

  Fly   181 T-SGMFGMR--PLVLFTSDESHYSFVKAANWLGLGSYNCVSVR-------TNER------GQMLL 229
            | ||....:  ..:::.||:|.....:.          |:|.|       |:|:      ...||
 Worm   274 TDSGKERSKNADYIVYCSDDSQVPLKEP----------CISCRVKLRKVITDEKNGSGMTSANLL 328

  Fly   230 DDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKN 294
            ..:|..|    |||..|..:....|:..:.|.|:|.....|:....:|||:||...|...|.:.:
 Worm   329 KQMEKDI----ARGFTPLVIIANYGSANIAANDEIWDLVTVSRSKKIWLHLDASYAGCEWLDSNS 389

  Fly   295 RSLIAGLERANSFSWNPHKTI----GAPLQCSLFLTRESGRL--LERCNSTEAHYLFQQDKFYDV 353
            |:             |.|..|    ...:.|| .|...|||:  :..|...|..
 Worm   390 RN-------------NVHALISEVHSVHITCS-SLFPYSGRISVVWSCEKLELD----------- 429

  Fly   354 SYDTGNKSVQCGRKI----DAFKFWLMLKARGYGKYGLMVDHAIHIARLLEGKLRQRGDRFRLVI 414
                       |.||    ...:.|::::..|.......|...|.:......::......|.:
 Worm   430 -----------GAKILYGEHPIRLWILIRLHGIRSIREAVKRKIILGNAFSERMSHHSQLFEM-- 481

  Fly   415 PEH--EYSNVCFWFIPKAMRVSSEEETPEWWSRLYTVAPKIKEQMAHSGTLMIG----YSPLKAK 473
             .|  |:....|.:..|.::..:|:..        .:.......:..|.||...    :..:..|
 Worm   482 -HHTNEHGVTVFQYKNKKIKDRTEDTN--------KITSMFHNYLVLSSTLKFSIVSFHGKVLIK 537

  Fly   474 NLGNFFRMVFTCFPILKSKELDFILDEIERLGEKI 508
            ::.|:.|    |...:..:.:..:::.::...|.:
 Worm   538 SVVNYGR----CNLSIMDESVSTLVNSVDEFEEAL 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	GadA	56..507	CDD:439846	96/499 (19%)
hdl-2	NP_501539.3	AAT_I	125..527	CDD:450240	95/471 (20%)