Protein Alignment CG5618 and spl-1

DIOPT Version :10

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_499913.1
• Gene: spl-1 / 176857
• WormBaseID: WBGene00004981
• Length: 552
• Species: Caenorhabditis elegans
• Alignment Length: 421
• Identity: 98/421 - (23%)
• Similarity: 159/421 - (37%)
• Gaps: 100/421 - (23%)

  Fly    28 VFHLLRKEDTFCVDPQKWDKQKIVPFLQPDKLKELINLKVRETENCSLAEIEELCQQVIHYSVKT 92
            ||.||||.      |...||.:.....:..||.|.|:...::.:..|...|..|.|..|....|
 Worm    67 VFSLLRKL------PAVRDKIEKELAAEKPKLIESIHKDDKDKQFISTLPIAPLSQDSIMELAK- 124

  Fly    93 SHGRFHNQLFGQLDPFGLAGALVT----EAMN--GSTYTY---------EVAPVFSLIETEVIAT 142
               ::.:.....:|...::||:.|    |.:|  |..|..         :|.|....:|.|:|..
 Worm   125 ---KYEDYNTFNIDGGRVSGAVYTDRHAEHINLLGKIYEKYAFSNPLHPDVFPGARKMEAELIRM 186

  Fly   143 ICKL-AGYKEGDGIFAPGGSTSNMYGMVLARYKIAPEVKTSGMFGMRPLVLFTSDESHYSFVKAA 206
            :..| .|.::..|....||:.|    :::|.:.......:.|:  ..|::| ....:|.:|.|||
 Worm   187 VLNLYNGPEDSSGSVTSGGTES----IIMACFSYRNRAHSLGI--EHPVIL-ACKTAHAAFDKAA 244

  Fly   207 NWLGL-------GSYNCVSVRTNERGQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDI 264
            :..|:       .|.|.|.::..||   |:|.....:.     |..|.|.:        |..|.|
 Worm   245 HLCGMRLRHVPVDSDNRVDLKEMER---LIDSNVCMLV-----GSAPNFPS--------GTIDPI 293

  Fly   265 NGAADVTERHGLWLHVDACLGGAALLSAKNRS-LIAGLERAN----SFSWNPHKTIGAPLQCSLF 324
            ...|.:.:::|:.:||||||||..:....:.. ||...:..|    |.|.:.||....|...|:.
 Worm   294 PEIAKLGKKYGIPVHVDACLGGFMIPFMNDAGYLIPVFDFRNPGVTSISCDTHKYGCTPKGSSIV 358

  Fly   325 LTRESGRLLERCNSTEAHYLFQQDKFYDVS------YDT---------GNKSVQCGRKIDAFKFW 374
            :.|          |.|.|: ||   ::.|:      |.|         .|.:|.          |
 Worm   359 MYR----------SKELHH-FQ---YFSVADWCGGIYATPTIAGSRAGANTAVA----------W 399

  Fly   375 LMLKARGYGKYGLMVDHAIHIARLLEGKLRQ 405
            ..|.:.|..:|.......:...|:|..|:.:
 Worm   400 ATLLSFGRDEYVRRCAQIVKHTRMLAEKIEK 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	GadA	56..507	CDD:439846	89/393 (23%)
spl-1	NP_499913.1	DOPA_deC_like	138..501	CDD:99743	78/340 (23%)