Protein Alignment CG5618 and unc-25

DIOPT Version :10

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_499689.1
• Gene: unc-25 / 176713
• WormBaseID: WBGene00006762
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 213/515 - (41%)
• Similarity: 312/515 - (60%)
• Gaps: 27/515 - (5%)

  Fly     8 AETVDQIRDGLM--------DDW----KILENVFHLLRKEDTFCVDPQKWDKQKIVPFLQPDKLK 60
            |:..|.:.:.|:        .:|    :.|..:..:|.|   :..|....| |||:.|..|||::
 Worm     6 ADESDAVLENLIAKEILPQTGNWEGTEEFLNRIVQVLLK---YIKDQNDRD-QKILEFHHPDKMQ 66

  Fly    61 ELINLKVRETENCSLAEIEELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAGALVTEAMNGSTYT 125
            .|::|.:.|... ||.::.:.|:.|:...|:|.|.||.||:...||...:||..:|...|.:.:|
 Worm    67 MLMDLSIPEKPE-SLLKLVKSCEDVLRLGVRTGHPRFFNQISCGLDLVSMAGEWLTATANTNMFT 130

  Fly   126 YEVAPVFSLIETEVIATICKLAGY--KEGDGIFAPGGSTSNMYGMVLARYKIAPEVKTSGMFGMR 188
            ||:||||.|:|..|:|.:.:..|:  ::.||||||||:.:|:|.|..||:::.|..|..||..:.
 Worm   131 YEIAPVFILMEKSVMARMWEAVGWDPEKADGIFAPGGAIANLYAMNAARHQLWPRSKHLGMKDIP 195

  Fly   189 PLVLFTSDESHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEAKIAEAKARGGEPFFVNCTA 253
            .|..|||::||||...|:..||:|:..|.::.|::.|:|:.:.|||||.|.|..|..|||..|||
 Worm   196 TLCCFTSEDSHYSIKSASAVLGIGADYCFNIPTDKNGKMIPEALEAKIIECKKEGLTPFFACCTA 260

  Fly   254 GTTVLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKNRSLIAGLERANSFSWNPHKTIGAP 318
            |:||.||||.:...|::.|||.||.||||..||..|||.::|..:||:|||||.:|||||.:||.
 Worm   261 GSTVYGAFDPLERVANICERHKLWFHVDAAWGGGMLLSPEHRYKLAGIERANSVTWNPHKLMGAL 325

  Fly   319 LQCSLFLTRESGRLLERCNSTEAHYLFQQDKFYDVSYDTGNKSVQCGRKIDAFKFWLMLKARGYG 383
            ||||..|.|:.| ||.:||...|.|||||||.||||:|||:|::||||..|.||.|||.|::|..
 Worm   326 LQCSACLFRQDG-LLFQCNQMSADYLFQQDKPYDVSFDTGDKAIQCGRHNDVFKLWLMWKSKGME 389

  Fly   384 KYGLMVDHAIHIARLLEGKLRQRGDRFRLVIPEHEYSNVCFWFIPKAMRVSSEEETPEWWSRLYT 448
            .|...::..:.:|.....::::. :.|.|:|...|:.|:|||::|..:|   ..|..|..:||..
 Worm   390 GYRQQINKLMDLANYFTRRIKET-EGFELIIENPEFLNICFWYVPSKIR---NLEPAEMRARLEK 450

  Fly   449 VAPKIKEQMAHSGTLMIGYSPLKAKNLGNFFRMVFTCFPILKSKELDFILDEIERLGEKI 508
            :|||||..|...||.|:||.|.|.:  .|||||:.:...|.: ::|||::.||..:||.:
 Worm   451 IAPKIKAGMMQRGTTMVGYQPDKQR--PNFFRMIISNQAITR-EDLDFLIKEIVDIGESL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	GadA	56..507	CDD:439846	199/452 (44%)
unc-25	NP_499689.1	DOPA_deC_like	102..503	CDD:99743	184/408 (45%)