Protein Alignment CG5618 and gad2

DIOPT Version :10

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_017950266.1
• Gene: gad2 / 100493806
• XenbaseID: XB-GENE-976598
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 472
• Identity: 206/472 - (43%)
• Similarity: 305/472 - (64%)
• Gaps: 16/472 - (3%)

  Fly    43 QKWDKQ-KIVPFLQPDKLKELINLKVRETENCSLAEIEELCQQVIHYSVKTSHGRFHNQLFGQLD 106
            |.:|:. |::.|..|::|.:..|.::.|... ||..|...|:..:.|::||.|.|:.|||...||
 Frog   127 QTFDRSTKVIDFHYPNELLQAYNWELSEQPQ-SLDGILLNCKTTLKYAIKTGHPRYFNQLSTGLD 190

  Fly   107 PFGLAGALVTEAMNGSTYTYEVAPVFSLIETEVIATICKLAGYK--EGDGIFAPGGSTSNMYGMV 169
            ..|||...:|...|.:.:|||:||||.|:|...:..:.::.|:.  .|||||:|||:.||:|.|:
 Frog   191 MVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREMIGWPGGSGDGIFSPGGAISNLYAML 255

  Fly   170 LARYKIAPEVKTSGMFGMRPLVLFTSDESHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEA 234
            :||:|:.||||..||..:..||.|||:.||:|..|.|..||:|:.:.:.::.:|||:::..|||.
 Frog   256 IARFKMFPEVKEKGMAALPRLVAFTSEHSHFSVKKGAAALGIGTDSVILIKADERGRLIPSDLER 320

  Fly   235 KIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKNRSLIA 299
            :|.|||..|..||||:.||||||.||||.:...||:.:::.:|:||||..||..|:|.|::..:.
 Frog   321 RIIEAKQNGYVPFFVSATAGTTVYGAFDPLVSIADICKKYRIWMHVDAAWGGGLLMSRKHKWKLN 385

  Fly   300 GLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFYDVSYDTGNKSVQC 364
            |.:||||.:|||||.:|.|||||..|.||.| |::.||...|.|||||||.||:|||||:|::||
 Frog   386 GADRANSVTWNPHKMMGVPLQCSALLVREEG-LMQNCNQMHASYLFQQDKHYDLSYDTGDKALQC 449

  Fly   365 GRKIDAFKFWLMLKARGYGKYGLMVDHAIHIARLLEGKLRQRGDRFRLVI---PEHEYSNVCFWF 426
            ||.:|.||.|||.:|:|...:...:|..:.::..|..|::.| :.:.:||   |:|  :|||||:
 Frog   450 GRHVDIFKLWLMWRAKGTTGFEAHIDKCLELSEYLYNKIKNR-EGYEMVIEGKPQH--TNVCFWY 511

  Fly   427 IPKAMRVSSEEETPEWWSRLYTVAPKIKEQMAHSGTLMIGYSPLKAKNLGNFFRMVFTCFPILKS 491
            :|.::|  :.|:..|..:||..|||.||.:|...||.|:.|.|...|  |||||||.: .|....
 Frog   512 VPPSLR--NMEDNEERMNRLSKVAPIIKARMMEYGTTMVSYQPHGDK--GNFFRMVIS-NPAAAH 571

  Fly   492 KELDFILDEIERLGEKI 508
            :::||:::||||||:.:
 Frog   572 QDIDFLIEEIERLGQDL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	GadA	56..507	CDD:439846	202/455 (44%)
gad2	XP_017950266.1	Pyridoxal_deC	141..512	CDD:395219	168/375 (45%)