Protein Alignment CG5618 and gad1.2

DIOPT Version :10

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_012819752.1
• Gene: gad1.2 / 100145511
• XenbaseID: XB-GENE-5830282
• Length: 554
• Species: Xenopus tropicalis
• Alignment Length: 510
• Identity: 225/510 - (44%)
• Similarity: 324/510 - (63%)
• Gaps: 34/510 - (6%)

  Fly     6 DGAETVDQIRDGLMDDWKILENVFHLLRKEDTFCVDPQKWDKQKIVPFLQPDKLKELI---NLKV 67
            :|.:..:|.   |::..:||.|  |:.:..|         .:.|::.|..|.:|.|.:   ||::
 Frog    68 NGEKCTEQF---LIEVLRILLN--HIKKTYD---------GESKVLDFHHPHQLLEGLEGFNLEL 118

  Fly    68 RETENCSLAEIEELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAGALVTEAMNGSTYTYEVAPVF 132
            .:... .|.:|...|...:.||:||.|.|:.|||...||..||||..:|...|.:.:|||:||||
 Frog   119 SDQPE-PLEQILVDCSDTLKYSIKTGHPRYFNQLSCGLDIIGLAGEWLTATANTNMFTYEIAPVF 182

  Fly   133 SLIETEVIATICKLAGY--KEGDGIFAPGGSTSNMYGMVLARYKIAPEVKTSGMFGMRPLVLFTS 195
            .::|..|:..:.::.|:  .|.||||:|||:.||:|.:..||||..|.|||.||..:..:|:|||
 Frog   183 IIMEEIVLKKMQEIIGWGENEADGIFSPGGTISNLYSLQAARYKYFPMVKTKGMAALPQIVIFTS 247

  Fly   196 DESHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGA 260
            ::|||||.||:..||:|:.|.::::.:|||:|:..|||.||.:||.:|..||:|:.||||||.||
 Frog   248 EQSHYSFKKASAILGIGTDNVIAIKCDERGKMIPSDLEDKILKAKRQGQHPFYVSATAGTTVYGA 312

  Fly   261 FDDINGAADVTERHGLWLHVDACLGGAALLSAKNRSLIAGLERANSFSWNPHKTIGAPLQCSLFL 325
            ||.:...||:.:|:|||:||||..||..|||.|:|..:.|:|||||.:|||||.:|.|||||..|
 Frog   313 FDPLITIADICKRYGLWMHVDAAWGGGLLLSKKHRYKMNGIERANSVTWNPHKIMGVPLQCSAIL 377

  Fly   326 TRESGRLLERCNSTEAHYLFQQDKFYDVSYDTGNKSVQCGRKIDAFKFWLMLKARGYGKYGLMVD 390
            .|:.| ||:.||...|.||||.||.||.:||||:|::||||.:|.||.|||.||:|...:.|.::
 Frog   378 IRQKG-LLQACNQQCADYLFQMDKPYDTAYDTGDKTIQCGRHVDIFKLWLMWKAKGSCGFELQIN 441

  Fly   391 HAIHIARLLEGKLRQRGDRFRLVIPEH-EYSNVCFWFIPKAMRVSSEEETP---EWWSRLYTVAP 451
            ..:.::..|..||:.:.: |.||..:. ||:|||||:||.::     |..|   ||.:||:.:||
 Frog   442 RCLELSEYLYNKLQSKSN-FELVFRDKPEYTNVCFWYIPPSL-----EHVPRDKEWKARLHKIAP 500

  Fly   452 KIKEQMAHSGTLMIGYSPLKAKNLGNFFRMVFTCFPILKSKELDFILDEIERLGE 506
            :||.:|...||:|:.|.|...|  .|||||||: .|..|..::||:|:||||||:
 Frog   501 QIKARMMEEGTVMVSYQPQGDK--PNFFRMVFS-NPASKKSDVDFLLEEIERLGK 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	GadA	56..507	CDD:439846	215/460 (47%)
gad1.2	XP_012819752.1	Pyridoxal_deC	104..478	CDD:395219	178/376 (47%)