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Protein Alignment Spn77Ba and SERPINB7

DIOPT Version :9

Sequence 1:	NP_649205.3	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_003775.1	Gene:	SERPINB7 / 8710	HGNCID:	13902	Length:	380	Species:	Homo sapiens

Alignment Length:	402	Identity:	104/402 - (25%)
Similarity:	190/402 - (47%)	Gaps:	45/402 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 LVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINV- 132
            :.|::....:|..:|.:  .::..:.|.:...|..|:::.|.|:..|::.::.:|:.|.|.:|.
Human     1 MASLAAANAEFCFNLFR--EMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTA 63

  Fly   133 --------EDEKLRGAYKVWSSFLNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQN-YNVQPME 188
                    ....|:...|...|.:|.:....:::.:..::..|.|....:|.:..:. |:.:...
Human    64 SGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVER 128

  Fly   189 VDF--YSPDSVIQINEDTNRTTRGLIPYTILPQDVYG-------AKMFLLSSLYFKGQWKFPFNK 244
            |||  :..|:...||:.....|.|.|      ::|.|       |.|.|::::||||:|:..|.|
Human   129 VDFTNHLEDTRRNINKWVENETHGKI------KNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTK 187

  Fly   245 TLTREEPFFSESGEVIGK-IPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFK 308
            :.|....|  :|.:..|| :.||.||..| .:|.:|.....:|||.|  ...:.|.|:||:.  .
Human   188 SETINCHF--KSPKCSGKAVAMMHQERKF-NLSVIEDPSMKILELRY--NGGINMYVLLPEN--D 245

  Fly   309 LNDVANNLKALGLRPILQRLAAFRN-RASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDEN 372
            |:::.|.|       ..|.|..:.| |......|||..|:|....::.:|..|..:|::|:|||:
Human   246 LSEIENKL-------TFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDES 303

  Fly   373 TANLDRMSSG--LFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLLNRPFQYMIVEKAT 435
            .|:|..::||  |:...::|.:.|.|.|:||.|.|.|.:.:..|..|...|......::.|.:..
Human   304 KADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRADHPFLFVIRKD 368

  Fly   436 GLLLFAGQVRNP 447
            .::||:|:|..|
Human   369 DIILFSGKVSCP 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_649205.3	serpin77Ba-like_insects	72..447	CDD:381062	102/397 (26%)
SERPINB7	NP_003775.1	serpinB7_megsin	1..380	CDD:381032	103/400 (26%)

Information from Original Tools:

Software error:

Can't use an undefined value as an ARRAY reference at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 1034.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.