DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and si:ch211-186e20.7

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_021329695.1	Gene:	si:ch211-186e20.7 / 566630	ZFINID:	ZDB-GENE-110407-6	Length:	410	Species:	Danio rerio

Alignment Length:	453	Identity:	132/453 - (29%)
Similarity:	200/453 - (44%)	Gaps:	65/453 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LMLWIPLLLG-AIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVS 71
            ::|||   .| ||.:|     .||..||..   |::|                        .|.|
Zfish     6 VLLWI---FGFAIVVC-----GNQETLQQP---PISA------------------------KLPS 35

  Fly    72 ISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEK 136
            :.....|||..|.:|:....:..:|:...|||||...|..|..|:.|:|:.||...:..|.....
Zfish    36 LINMNNDFAFHLYKRVIESPDYQSKNIFFSPFSVSIALSELSLGAGGDTKQQLLSGIGYNSTTFS 100

  Fly   137 LRGAYKVWSSFL----NITTSTIEVATLQAIYTGKGY-PIKNNYRDAIQNYNVQPMEVDFYSPDS 196
            ....::::.|.|    |.|...|:|.|  |:|....: |......|..:.|:.....|||...::
Zfish   101 TEEMHQLFHSLLEDIGNRTGVDIDVGT--ALYASDRFKPHSKFLEDMKEFYHSDGFTVDFRVKET 163

  Fly   197 VIQINEDTNRTTRGLIPYTI--LPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEV 259
            |.|||....:.|:|.....:  |.:|..   ||||:.:||||:|..||....|||..|..:....
Zfish   164 VDQINNYAKKKTQGKFNQAVDDLEEDTL---MFLLTYIYFKGKWDKPFKPEKTRESTFHIDDKTT 225

  Fly   260 IGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLP--KRGFKLNDVANNLKALGLR 322
            : .:.||.|........:.| |...||.|.|  :|..:|.:.:|  |...|      |:|.|.:.
Zfish   226 V-PVQMMHQYERLKVFYDAE-LSTKVLCLDY--KDSFSMFLAVPDDKMEHK------NIKDLEMT 280

  Fly   323 PILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMS-SGLFAK 386
            ...|....:| |::....|::.:||....|.::||.:|..||:.|:|.:. ||...:| ..:|..
Zfish   281 VSRQHFEKWR-RSAFKKTVDIYVPKLSLKTSYSLKDILKGMGMADMFSDK-ANFTGVSEEKIFVS 343

  Fly   387 LVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLL--NRPFQYMIVEKATGLLLFAGQVRNP 447
            .|:|...:.:|||||||.|||..::..:...|..:|  ||||...|.::....:||.|:|.||
Zfish   344 KVLHKATLDIDEQGTTAAAVTGVSMRVRLHNPLSILKFNRPFMVFITDQTNDNILFFGKVVNP 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	114/380 (30%)
si:ch211-186e20.7	XP_021329695.1	alpha-1-antitrypsin_like	39..403	CDD:239011	114/380 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920