Protein Alignment gogo and Thsd1

DIOPT Version :10

• Sequence 1: NP_649200.2
• Gene: gogo / 40225
• FlyBaseID: FBgn0052227
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: NP_062522.1
• Gene: Thsd1 / 56229
• MGIID: 1929096
• Length: 851
• Species: Mus musculus
• Alignment Length: 1038
• Identity: 210/1038 - (20%)
• Similarity: 329/1038 - (31%)
• Gaps: 327/1038 - (31%)

  Fly    36 SSIMLLLLSGTSHVLAVRKGRLMSPSTFTALSGDLHVQIQFNGNEMSSQAEEEHTIGGGPSNEEP 100
            |:::|::|  ..:||...:..|:......||| |..|.:.|:                      .
Mouse     9 SNLLLVVL--CDYVLGEAEYLLLQEPVHVALS-DRTVSVGFH----------------------Y 48

  Fly   101 LSSSDGLKSRNNTIMSTLVISKIIDEVESPLEKGLTPGPEVTNTSQVVLHRKRKEVVQNIPLFPD 165
            ||..:| ..||.::|..          |:...:.||....:||.:|..|.
Mouse    49 LSDVNG-TLRNVSVMLW----------EANTNRTLTTKYLLTNQAQGTLQ--------------- 87

  Fly   166 PRFNVTQVTVPCQTFLIGGRYEMQVVSNLKSVNRSEVTT--TLVPAQDERLHQTLDVRWP----- 223
                     ..|..|...|.|...::        .|||.  |.||..::...  |.|.||
Mouse    88 ---------FECFYFKEAGDYWFVMI--------PEVTDNGTQVPLWEKSAF--LKVEWPVFHID 133

  Fly   224 ---SAEMIVSPVRLKTYPKHPVEVTLRFPEVNCNQSGSLALPEFWLELIYCGKDRSCNRNITPTS 285
               :|:......::..:...|:   ..||         :..|:..:::|:..:......::....
Mouse   134 LNRTAKAAEGTFQVGVFTTQPL---CLFP---------VDKPDMLVDVIFTDRLPEARASLGQPL 186

  Fly   286 VLFAEQIRGFPKNKSLHLGCELFGLAGNYAVQLRPMIPAQNVPTTRRLLSVDWSDEFVFNVYARS 350
            .:.|.:.....:.:.:..||...|:.....|.||.:.....:.:|.   .:|.:.:|.:.:....
Mouse   187 EIRASKRTKLTQGQWVEFGCAPVGVEAYVTVMLRLLGQDSVIASTG---PIDLAQKFGYKLMMAP 248

  Fly   351 IFPCDPHTGIGVLYEYPGCILEQGDRVRLYARLRADVASLKPPTSLHYVSEQRVVKSQHSLYFAC 415
            ...|:....:.||  .|.|:..|| .:.:|..     |..:|......|:|.|:...:....|.|
Mouse   249 EVTCESVLEVMVL--PPPCVFVQG-VLAVYKE-----APKRPEERTFQVAENRLPLGERRTVFNC 305

  Fly   416 EHFSEKYVEYCFVY--VSQAISGAVADVRMDCVPTLPVSDSDTGGWGPWSEWTPCSTNCLGGTRN 478
            ..|.....:|||.:  |.:....|     .:|:  |...:.:|  ||||..|:||||.|....|.
Mouse   306 TLFDVGKNKYCFNFGIVKKGHFSA-----KECM--LIQRNIET--WGPWQPWSPCSTTCGDAVRE 361

  Fly   479 RYRFC-DSPPPRYGAKFCEGPSVETQKCGKSIADTWDCIYETSGTVITKENSTEVSQEIGPGCRC 542
            |.|.| .|.|.|   ..|.|.|.||..|...     :|      .|......:.||.:
Mouse   362 RRRLCVTSFPSR---PSCSGMSSETSPCSLE-----EC------AVFRPPGPSPVSPQ------- 405

  Fly   543 GCIVHLGSSKPKRIIAGATQSCPGRSFWLIQVDGEESISLALSFLRLP-CATQYIKVRDGPSLSS 606
                  ...|...::     :..|.|..|..:.....|:|...|.|.| |:|   .||.. |:.|
Mouse   406 ------DPVKSNNVV-----TVTGISLCLFIIFATVLITLWRRFGRAPKCST---PVRHN-SIHS 455

  Fly   607 TLLVELNGGGLILKGAGVPVVVDSTGGQLLVEFS--------AGDGPAGNATQEASPACTG---- 659
                              |....::..:.:.|.|        |||||.|      ||..||
Mouse   456 ------------------PGFRKNSDEENICELSEPRGSFSDAGDGPRG------SPGDTGIPLT 496

  Fly   660 -----------------GFMANVQQ--------RLATRS----SNSSITLVAATRLSGKTRSVVH 695
                             .|.:|.|:        |||.:.    ....:|         :|..|.|
Mouse   497 YRCSASAPPEDEASGSESFQSNAQKIIPPLFSYRLAQQQLKEMKKKGLT---------ETTKVYH 552

  Fly   696 KSMSRLRFTLVHLSAM----------IFASIIIIISSLL---GAQYVVRYRKYHLAVARRQDEGS 747
            .|.|.|..|:|..:|.          ..||...|.|..|   ||                 ..|.
Mouse   553 VSQSPLTDTVVDATASPPLDLECPEEAAASKFRIKSPFLDQPGA-----------------GTGE 600

  Fly   748 RLHTPRASLSSLQGPPSRAMSTTTLLSEVIYMVKMR---------PKHHLRHSILRESVDAENLT 803
            |   |.:.|..:..||..|:|.:..|   |...::|         .:.|.|.|:.|.:.......
Mouse   601 R---PPSRLDGIVPPPGCAVSPSQTL---IRKSQIRSTGGRDGSSERCHSRSSLFRRTASFHETK 659

  Fly   804 KETEFKESDSQGMLAKCAEIKELGS-----------------SASMVTLRNER-------SSPAR 844
            :...|:|.....:..:  ::....|                 |..::..|.|.       |||..
Mouse   660 QSRPFRERSLSALTPR--QVPAYSSRMRTWDQMEDRCRPPSRSTHLLPERPEHFQGAGRTSSPLG 722

  Fly   845 SLDTGSIIG------SPSSAEAELAAVHSRSE----------SKDSPSDEPIEPPSCKDSARDSE 893
            .|.....:|      .|...:|.|.|...:.|          |..|.|.:...|...|||.:...
Mouse   723 PLSKSYTVGHPRRKPDPGDRQAGLVAGAEKMEPHRAHRGPSPSHRSASRKQSSPIFLKDSYQKVS 787

  Fly   894 SIISSGM-SSLCNSPPMN---------SKRLSKYSDRYDAVTLKLLSSRLDESLQDASSLLSV 946
            .:..|.. ...|.|.|::         |.||::...|...:.....|:..||:    :|.|||
Mouse   788 QLSPSHFRKDKCQSFPIHPEFAFYDNTSFRLTEAEQRMLDLPGYFGSNEEDET----TSTLSV 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gogo	NP_649200.2	TSP1	459..505	CDD:214559	22/46 (48%)
		CUB	<570..640	CDD:412131	14/70 (20%)
Thsd1	NP_062522.1	PTZ00441	<289..>406	CDD:240420	41/152 (27%)
		TSP1	342..391	CDD:214559	23/56 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	471..516		11/50 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	626..646		2/19 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	682..777		17/94 (18%)